High hemoglobin

When clinically diagnosing whether liver function is healthy, hemoglobin is a very important reference data. If hemoglobin is too high, it is necessary to consider whether it is caused by liver damage. Because of the importance of the liver to the human body, if your hemoglobin is abnormal, please be sure to pay attention to a more detailed diagnosis to see if it is caused by liver disease.

The most common clinical situation is high hemoglobin, and its appearance is not accompanied by certain physical symptoms. Many friends know that their hemoglobin is high, usually during physical examinations. So, what factors can cause high hemoglobin? Here is an analysis for you:

High hemoglobin levels are common in compensatory increases such as lung disease and heart disease. Residents of the plateau area. Physiological increases include newborns and males with vigorous blood production. Physical labor. Dehydration. Hematopoietic system diseases, such as myelofibrosis, polycythemia vera, etc.

The liver has the functions of uptake, conjugation and excretion in bilirubin metabolism. Any one or several dysfunctions can cause jaundice. Checking bilirubin metabolism is important for determining liver function, especially for identifying jaundice.

Bilirubin determination includes total bilirubin and direct bilirubin. The normal values ​​are: total bilirubin 4-19μmol/L, direct bilirubin 0-7μmol/L. The difference between the two is indirect bilirubin. In liver disease, bilirubin concentration increases significantly, often reflecting more severe liver cell damage.

In cholestatic jaundice, direct bilirubin cannot be excreted by hepatocytes and bile ducts, resulting in a significant increase in serum direct bilirubin, and its proportion in total bilirubin increases significantly; in hepatocellular jaundice, due to the simultaneous impairment of hepatocyte uptake, conjugation, and excretion, the serum direct bilirubin/total bilirubin ratio increases, but the increase is not as obvious as in cholestatic jaundice; clinically, the diseases that cause increased indirect bilirubin mainly include hemolysis, Gilbert's disease, and bypass bilirubinemia.

After understanding what diseases may cause high hemoglobin, if your condition is caused by liver damage, it is recommended that you seek timely treatment. In addition, if your hemoglobin is only high but your liver is not damaged, it is recommended that you pay attention to protecting your liver health and avoid drinking alcohol to avoid liver disease.