As people pay more attention to some serious diseases in their lives, gout has gradually become the focus of people's attention. So, what happens if gout is severe? The following article will analyze it for you. 1. Gout stones: The formation of tophi is the result of tissue damage caused by long-term hyperuricemia; it is deposited in the joint capsule, affecting joint movement; it can cause "punch-hole"-like damage to the bone, and in severe cases, it can lead to fractures. 2. Kidney stones and kidney pain: About 10-20% of patients with primary gout have kidney stones, and may suffer from renal colic and hematuria. Renal interstitial inflammation and renal vascular damage occur, leading to renal insufficiency. 3. Damage to the kidneys: Urate deposition in the kidneys causes renal disease, including chronic uric acid nephropathy (uric acid nephropathy, gouty nephropathy, gouty interstitial nephritis), acute uric acid nephropathy (renal tubular uric acid deposition), and uric acid kidney stone formation. 4. Joint disability: Repeated attacks lead to chronic gouty arthritis, which in turn causes attacks to become more frequent and the intervals between attacks to become shorter. 5. Life-threatening: 50% of gout patients have hypertension, 30% of gout patients have diabetes, 70% of gout patients have dyslipidemia, and 75% of gout patients have obesity. The chance of gout patients developing coronary heart disease is twice that of non-gout patients, and it is considered to be coronary heart disease. |
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