Glycated hemoglobin

We all know that glycated hemoglobin is produced by the combination of hemoglobin in red blood cells and blood sugar. Most of our friends in life suffer from diabetes. Glycated hemoglobin is an indicator of the overall blood sugar control of diabetic patients. It is of great significance for judging the different stages of diabetes. However, glycated hemoglobin cannot be the basis for diagnosing diabetes, but it can be used as a health check item for diabetes.

Glycated hemoglobin affects our human body in many aspects. For example, it can change the affinity of red blood cells for oxygen and cause increased blood lipids and blood viscosity. It is an important cause of cardiovascular disease. Therefore, we should all know more about glycated hemoglobin.

The product of the combination of hemoglobin in red blood cells in human blood and blood glucose is glycated hemoglobin. The combination of blood glucose and hemoglobin to produce glycated hemoglobin is an irreversible reaction, which is proportional to the blood glucose concentration and remains for about 120 days, so the blood glucose concentration 120 days ago can be observed. The English code for glycosylated hemoglobin is HbA1c. The glycated hemoglobin test can usually reflect the patient's blood sugar control over the past 8 to 12 weeks.

Normal glycated hemoglobin is below 6%. It accounts for less than 6% of the total hemoglobin. However, it is not easy to keep glycated hemoglobin below 6% for a long time. Whether you can stick to diet and exercise is one thing.

If someone has certain comorbidities, exercise can only be reasonably managed on this basis. Fat people cannot accept all strenuous exercises. In addition, as the disease progresses, the cellular function of insulin is also constantly failing. Therefore, long-term good blood sugar control requires lifelong efforts from doctors, nurses, nutritionists, patients, and their families. So in the United States this indicator is below 7%. China’s target is below 6.5%.

We call on everyone to achieve the glycated hemoglobin standard within one year after being diagnosed with diabetes. The earlier the standard is achieved, the fewer long-term complications there will be. The sooner you meet the standard, the more likely it is that high blood sugar and high blood lipids will continue to damage your embryonic cells and the damage to various tissues and target organs in the human body will be reduced. Otherwise it will last long. Therefore, it is required that within one year, you can actively cooperate with the doctor to achieve the standard, and then persist in it for a long time.

But for some patients, their glycated hemoglobin may be 10% or 12% when diagnosed. Maybe they will think I have no confidence because the difference is so big. Finally, we conducted a scientific analysis and found that under what conditions of blood sugar levels will lead to fewer complications. We call this evidence-based medicine. The results show that if you can get your glycosylated hemoglobin to the standard within one year, your future complications will be significantly reduced. Your blood sugar is very high, and for every 1% drop in your blood sugar level from 10 to 12, if you work hard and you drop 1%, your microvascular disease can be reduced by 7% and your large vessel myocardial infarction can be reduced by 14%. This is what I call the most well-known UK Prospective Diabetes Study.

The observation period was from 1977 to 1997, with an average of ten years per person. The research results confirm that doctors should treat the disease accordingly. The other group must have significantly reached the glycated hemoglobin standard. The final results analyzed that for these two groups of patients, the microvascular and macrovascular complications of the group receiving intensive treatment were significantly reduced. This tells us that if you can reduce it to below 6, that is best; below 6.5 is also acceptable; below 7 is still acceptable. It is best if you can reduce it to the best. If you cannot reduce it to the best, your efforts step by step will lead to results for each step.

After reading the article's explanation of the relevant knowledge about glycated hemoglobin, I believe everyone has a general understanding of glycated hemoglobin. People must know some knowledge about it, pay more attention to their bodies, and develop a good habit of regular physical examinations to effectively protect our health.