What is the treatment for chronic glomerulonephritis?

Nephritis is a type of kidney disease and is relatively common in life. There are many types of nephritis. Glomerulonephritis is one of them. So what is the treatment for glomerulonephritis?

Treatment of glomerulonephritis

There is no specific drug to treat this disease, and it is a self-limiting disease. Therefore, symptomatic treatment is basically the main treatment. When chronic nephritis attacks acutely, it should be treated according to the treatment principles of acute nephritis. When there is a large amount of proteinuria, it should be treated according to the treatment principles of nephrotic syndrome. The necessary steps are to prevent water and sodium retention and control circulating blood volume, so as to alleviate symptoms, prevent fatal complications (heart failure, hypertensive encephalopathy), protect renal function, prevent various inducing and aggravating factors, and promote the repair of renal pathological histology and function.

1. General treatment: Rest in bed after acute onset. The dietary principle is mainly low-salt, high-vitamin, high-calorie diet. Protein intake should be maintained at 40-70 g/day. Salt intake should be 2-3g/D, and the intake of high potassium foods should be limited.

2. Symptomatic treatment: For diuresis, thiazide diuretics are commonly used; for antihypertensive drugs, thiazide diuretics and vasodilators are commonly used. Ganglion blockers can be used when necessary, or calcium channel blockers can be added; for the treatment of hyperkalemia, it is mainly to limit high-potassium diet and use potassium-excreting diuretics.

3. Treatment of complications: To control heart failure, the focus of treatment should be on correcting water and sodium retention and restoring blood volume, rather than using digitalis drugs to strengthen myocardial contractility, that is, the main measures are diuresis and blood pressure reduction; for hypertensive encephalopathy, sodium nitroprusside and other drugs can be intravenously infused, and convulsions can be treated with intravenous diazepam; for uremia, refer to "acute renal failure"

4. Treatment of infection foci: It is currently advocated that when the bacterial culture of the lesion is positive, antibiotic treatment should be actively used. Penicillin or macrolide antibiotics are commonly used to control the infection lesions and prevent the spread of bacteria for about 2 weeks or until cured. Tonsillectomy has no definite effect on the course of acute nephritis.

5. Anticoagulation and thrombolysis: intravenous drip of urokinase, supplemented with diuretics and potassium supplements.

6. Dialysis treatment: Dialysis treatment should be used when acute nephritis occurs in the following situations: severe water and sodium retention; acute renal failure, oliguria for more than 2 days, hyperkalemia, acute left heart failure, and severe acidosis.