How to check for gout, detection methods for gout

Gout is a joint disease that is common in middle-aged and elderly people. Gout attacks can make people feel very uncomfortable because redness and swelling will appear in the joints. Sensations such as tingling. What we need to do for gout is early detection and early treatment, and detect gout in time through some professional examination methods.

1: Checking for gout requires routine differential examination methods. Experts point out that if a gout patient has a fever, blood culture should be done to rule out infection. Joint cavity puncture and fluid extraction for culture can not only differentiate it from other arthritis, but also determine whether it is gout.

1: Routine blood test and erythrocyte sedimentation rate are common examination methods, which are very effective for examining acute gout. Experts point out that the patient's peripheral blood white blood cell count is elevated, usually (10-20)×109/L, and rarely exceeds 20×109/L. Neutrophil counts increased accordingly. People with decreased renal function may have mild to moderate anemia.

1: When acute gouty arthritis occurs, fluid may accumulate in the swollen joint cavity. Extracting synovial fluid with an injection needle for examination is of extremely important diagnostic significance. Even in the asymptomatic period, sodium urate crystals can be found in many joints. Urate crystals can be found in more than 95% of synovial fluid in acute gouty arthritis.

1: In the case of a purine-free diet and without taking drugs that affect uric acid excretion, the total uric acid content in the urine of a normal male adult within 24 hours does not exceed 3.54mmol/(600mg/24h). 90% of primary gout patients have uric acid excretion less than 3.54mmol/24h. Therefore, normal uric acid excretion cannot rule out gout, but uric acid levels greater than 750 mg/24 h indicate excessive uric acid production, especially non-renal secondary gout. When blood uric acid levels increase, uric acid levels also increase significantly.

1: Synovial fluid examination is a common method for checking gout. Experts point out that synovial fluid examination can be performed for swelling of larger joints such as ankles and knees in the acute stage. Birefringent needle-shaped sodium urate crystals can be seen in the white blood cells. Synovial fluid analysis can also help with diagnosis. The white blood cell count is generally between 100 and 7,000, and can reach 50,000, mainly segmented granulocytes.

1: During the acute attack phase, the serum uric acid level in most patients is elevated. It is generally believed that the uricase method has diagnostic value when the concentration is 416 μmol/L (7 mg/dl) for men and >357 μmol/L (6 mg/dl) for women. If uricosuric drugs or cortical hormones have been used, the serum uric acid level may not be high. The remission period can be normal. 2% to 3% of patients present with typical gout attacks but have serum uric acid levels lower than the above levels. There are three explanations: ① The temperature gradient between the core body temperature and the peripheral joint temperature is large; ② The body is in a state of stress and secretes more adrenal cortical hormones, which promotes the excretion of serum uric acid, while the sodium urate content in the distal joints is still relatively high; ③ The influence of treatment with uricosuric drugs or corticosteroids.

What we need to do is to go to the hospital in time, and after diagnosis through examination, carry out symptomatic treatment as soon as possible. Although such diseases are particularly difficult to cure, after treatment, the symptoms can be alleviated and the pain can be relieved.