What are the effects and functions of Eclipta prostrata?

The efficacy and function of dark lotus grass can be manifested in antibacterial issues, especially it has a good inhibitory effect on bacteria such as Staphylococcus aureus and Salmonella typhi. At the same time, it can also help us improve the body's immunity and fight diseases. It also has a good effect on the prevention of cardiovascular system diseases.

1. Antibacterial effect: The plate hole method was used to prove that Eclipta prostrata has antibacterial effect on Staphylococcus aureus, Bacillus typhi, Shigella sonnei, and Pseudomonas aeruginosa.

2. Hepatoprotective effect: benzene, acetone, petroleum ether and 50% ethanol extracts of Polygonum multiflorum all have protective effects on liver damage caused by carbon tetrachloride, among which 50% ethanol extract has the strongest effect. In the carbon tetrachloride-induced liver injury model in mice and rats, the ethanol extract of Helianthus annuus had a significant protective effect on liver function, as observed by indicators such as AST (aspartate aminotransferase), ALT (alanine aminotransferase), total protein, total bilirubin and increased clearance rate of titanium sulfobromide.

3. Effect on immune function: Oral administration of 10g/kg and 20g/kg of Eclipta prostrata decoction to mice can significantly increase the thymus weight of young mice, improve the carbon particle clearance rate of mice and the number of white blood cells in peripheral blood; significantly increase the degree of ear swelling of mice caused by 2,4-dinitrochlorobenzene (DNCB) and the delayed-type foot pad swelling of mice caused by sheep red blood cells (SRBC), and significantly increase the percentage of T lymphocytes in peripheral blood; but it has no significant effect on the secretory antibody function of mouse spleen cells and the content of serum hemolysin antibody. The above results indicate that Herba Lycoris Radiatae can significantly enhance nonspecific immunity and cellular immunity, but seems to have no effect on humoral immunity. The 20% enol extract of Eclipta prostrata significantly promoted the proliferation of T and B lymphocytes; the monomer compound S2S3S8 significantly promoted the transformation of lymphocytes and increased the production of interleukin II.

4. Anti-mutagenic effect: The water-soluble extract of Eclipta prostrata, 7.5g/kg, 15g/kg, and 30g/kg, administered or intraperitoneally to mice, had a significant inhibitory effect on cyclophosphamide-induced polychromatic erythrocyte micronuclei in mice, indicating that the drug has a certain protective effect on chromosome damage. The anti-mutagenic effect and enhancement of immune function of Eclipta prostrata may be part of the pharmacological basis of its kidney-tonifying and anti-aging effects.

5. Effect on the cardiovascular system: Eclipta prostrata can increase the coronary flow of guinea pigs' hearts and change the T wave of the electrocardiogram. It can significantly prolong the life span or improve the survival rate of mice under normal pressure or reduced pressure hypoxia conditions. This effect is consistent with the clinical trial of Eclipta prostrata extract in cases of coronary heart disease and angina pectoris.

6. Hemostatic effect: Cut the dog's femoral artery in half, apply the powder of the leaves of the black lotus to the bleeding area and apply a little pressure. It has a good hemostatic effect. The water extract also has a significant hemostatic effect.