What is demyelination of white matter?

Protein demyelination refers to the destruction of normal mature myelin. At this time, diseases such as protein demyelination are prone to occur. There are many such diseases, including multiple sclerosis, progressive multifocal proteinopathy, acute sporadic encephalomyelitis, and central pontine myelinolysis, etc. These are all relatively common diseases. There are many causes of this disease. It is a neurological disease, such as infection, poisoning and other reasons.

Causes

Many diseases can occur in the white matter of the brain. The typical response of white matter to various harmful stimuli is demyelinating changes, which can be a secondary manifestation of neurological diseases such as infection, poisoning, degeneration, trauma, infarction, etc. There is a group of demyelinating diseases of the central nervous system whose causes are still unclear.

Therefore, the current classification of this group of diseases can be divided into two major categories according to whether the myelin sheath is mature at the time of onset: ① demyelinating diseases with normal myelin sheath development, such as multiple sclerosis, progressive multifocal leukoencephalopathy, acute sporadic encephalomyelitis, etc.; ② poor myelin formation diseases, such as globoid cell-like leukodystrophy, metachromatic leukodystrophy, spongiform encephalopathy, etc.

Family treatment and care measures:

1. Treatment and medication: Treatment of this disease should be started as early as possible to control the deterioration of the disease and reduce recurrence. Commonly used drugs include prednisone, epinephrine, dexamethasone, methylprednisolone, etc. The doctor chooses the medicine based on the patient's condition, treatment response and financial situation.

2 Avoid triggers; trauma, fatigue, excitement, upper respiratory tract infection and other infections can induce aggravation and recurrence of the disease, so try to avoid them. Pregnancy can accelerate the progression of the disease, so women should avoid pregnancy for at least two years after an attack. 3 During the acute attack or relapse period: (1) Rest in bed to help relieve the symptoms; (2) Give the paralyzed limbs appropriate passive exercises to prevent joint stiffness and pain; (3) Bedridden patients in the late stage should be turned over frequently and receive skin care. 4 Follow-up examination: Patients should go to the hospital for follow-up examinations regularly to understand whether their condition has progressed so that appropriate treatment can be given.