Arrhythmia is a relatively common symptom. Many people do not pay much attention to this disease, which often leads to worsening of the disease and is very harmful to the health of the body. Arrhythmia will first cause poor blood circulation, which will cause symptoms of chest tightness and weakness. More severe cases will lead to bradycardia, which is also an important cause of sudden death. Therefore, we must be vigilant about arrhythmia and treat and recuperate in time. Are arrhythmias dangerous? 1. Arrhythmia can cause blood circulation disorders: When arrhythmia occurs, the contraction process of the atria and ventricles changes, which can cause cardiac output to drop by about 30%, causing the patient to experience symptoms such as guilty conscience, chest tightness, and weakness. 2. Severe arrhythmia can cause sinus arrest, sinoatrial block and bradycardia, resulting in tachycardia syndrome (also known as slow-fast syndrome) 3. Arrhythmia can lead to sudden death: The most common cause of sudden death is arrhythmia, among which ventricular tachycardia, ventricular fibrillation and conduction block have the highest incidence of sudden death. 4. The harm of arrhythmia to the human body is determined by the nature of the arrhythmia. Arrhythmia is an abnormality in the frequency and rhythm of the heart. The abnormality in the origin of cardiac excitation, the conduction time of excitation, and the order of conduction is called arrhythmia. Generally speaking, supraventricular arrhythmias without rapid ventricular rhythm are not fatal. The so-called malignant arrhythmias are mainly ventricular rapid arrhythmias that have a great impact on hemodynamics, such as ventricular tachycardia, ventricular fibrillation, ventricular flutter, etc. Commonly used antiarrhythmic drugs There are nearly 50 kinds of antiarrhythmic drugs in clinical use, but there is still no unified classification standard. Most scholars agree that antiarrhythmic drugs should be divided into the following four categories based on their different effects on the heart to guide rational clinical drug use. Class I drugs are further divided into three subcategories: A, B, and C. (1) Class I: sodium channel blockers. 1) Class IA moderately blocks sodium channels, including drugs such as quinidine. 2) Class IB mildly blocks sodium channels, including drugs such as lidocaine. 3) Class ⅠC obviously blocks sodium channels, and drugs of this class include propafenone. (2) Class II is β-adrenergic receptor blockers, which are effective because they block β receptors. The representative drug is propranolol. (3) Class III is a drug that selectively prolongs the repolarization process, including amiodarone. (4) Class IV: calcium channel blockers. They block calcium channels and inhibit Ca influx; representative drugs include verapamil. |
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