How does cholestatic urticaria occur?

How does cholestatic urticaria occur?

When it comes to urticaria, I believe everyone is familiar with it. Cholecalcitonin urticaria is one of the typical types. This type of eczema mainly occurs in young people. Having cholealkaline urticaria will affect our normal life. If it is serious, it will induce other diseases, and in severe cases it will even endanger human life. Since cholestatic urticaria is so harmful, what are the causes of cholestatic urticaria?

How does cholestatic urticaria occur?

More common in young people. It is mainly caused by exercise, heat, mental stress, hot drinks or alcoholic beverages, which trigger impulses in the choleretic nerves and release acetylcholine, increasing the level of cyclic guanosine monophosphate (cGMP) in alkaliphilic granulocytes and mast cells, leading to the release of histamine and the onset of the disease.

diagnosis

It is more common in young people and is often induced by exercise, heat, tension, hot food or drink, etc. It manifests as small wheals and itching, sometimes accompanied by systemic symptoms such as drooling, headache, abdominal pain, diarrhea, etc. It can be diagnosed by stimulating exercise or hot baths and intradermal injection of nicotinic acid picrate or methylphenidate bile salt to induce wheals.

treat

1. General treatment

Avoid triggers. Patients with cholestatic urticaria should keep their body cool, avoid sweating, heat, mental stress, hot drinks or alcoholic beverages, etc.

2. Oral medication

In addition to the regular use of antihistamines, atropine, propantheline, reserpine, etc. are often added to achieve more satisfactory therapeutic effects. Topical medications: In summer, you can choose anti-itching lotions, calamine lotion, etc. In winter, you can choose anti-itching emulsions (such as diphenhydramine cream).

prevention

Patients with cholestatic urticaria should keep their body cool, avoid sweating, heat, mental stress, hot drinks or alcoholic beverages, etc. Certain Chinese medicines, such as Polygonum multiflorum, wolfberry, ginseng, astragalus, ganoderma lucidum, jujube, Ligustrum lucidum, Cuscuta australis, Schisandra chinensis, Polygonatum sibiricum, Chinese yam, Codonopsis pilosula, etc., have multiple functions such as anti-free radicals, improving immune function, promoting metabolism, regulating the nervous system and endocrine system, and have obvious anti-allergic effects. People with allergies can choose one or two ingredients to make soup and drink as tea.

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