Can Cassia Seed Lower Blood Pressure?

Cassia seed is a common food therapy product in people's daily life, and it is also a product that many people use to soak in water and drink. Cassia seed has many functions and effects, lowering blood pressure is one of them. In addition to lowering blood pressure, Cassia seed also has anti-fungal, lipid-lowering, anti-platelet aggregation, liver protection and human immunity regulating effects.

1. Antibacterial effect

Cassia seed alcohol extract has inhibitory effects on Staphylococcus, diphtheria Corynebacterium, Salmonella typhi, Salmonella paratyphi, and Escherichia coli, while the water extract is ineffective.

2. Antifungal

The water extract was diluted by test tube method, 1:20 against Microsporum audouinensis, 1:10 against Trichophyton thunbergii and Microsporum gypseum.

3. Blood pressure reduction

Both aqueous and ethanol extracts have a hypotensive effect on anesthetized dogs, cats, and rabbits.

4. Lowering blood lipids

Feeding rats with 6g of Cassia seed decoction or Cassia seed powder for 8 weeks can reduce plasma cholesterol and triglycerides in rats with experimental hyperlipidemia, and reduce the triglyceride content in the liver.

5. Antiplatelet aggregation

Feeding rats with 6 g/kg of Cassia seed decoction or powder for 8 weeks had an inhibitory effect on ADP-induced platelet aggregation in rats.

6. Impact on immune function

Subcutaneous injection of 15g/kg of Cassia seed decoction and alcohol precipitation can cause thymus atrophy in mice, significantly reduce the negative rate of ANAE staining of peripheral blood lymphocytes, and inhibit the delayed-type hypersensitivity reaction of mouse skin caused by 2,4-dinitrochlorobenzene (DNCB), but have no obvious effect on serum hemolysin formation. In addition, Cassia seed decoction and alcohol precipitation can significantly increase the percentage and phagocytic index of chicken red blood cells phagocytized by mouse peritoneal macrophages, and the lysozyme level is also significantly higher than that of the control group.

7. Liver protection

Oral administration of 670 mg/kg of Cassia seed hot water extract has a weak detoxification effect on the liver of mice poisoned by carbon tetrachloride. Cassia seed was defatted with petroleum ether, extracted with chloroform, and then extracted with methanol. The results showed that the methanol extract had a significant liver-protecting effect. Further, chrysophanol-1O-triglucoside and chrysophanol-1-O-teglucoside were isolated from it, which had a weak protective effect on liver cells damaged by carbon tetrachloride at 1 mg/ml. It was also found that aloe-emodin had a similar anti-hepatotoxic effect.