The dangers of high uric acid

The emergence of diseases is very harmful to human health. When improving some diseases, we must choose the right method, which will be very helpful to the improvement of the disease and will not affect the patient's body. Among the common diseases, hypertension and diabetes have a great impact on the patient's body and mind. These diseases have serious restrictions on the patient's diet and work and rest. What are the hazards of high uric acid?

Many people are not very clear about the dangers of high uric acid levels, so we need to learn more about this type of disease so that when we want to improve it, we can know what methods to choose so that it will not cause harm to the body.

Dangers of high uric acid levels:

Uric acid is a product of purine metabolism in the human body. There are two sources of purine in the human body. The endogenous source depends on self-synthesis or nucleic acid degradation (about 600 mg/d), accounting for about 80% of the total uric acid in the body; the exogenous source is the intake of purine diet (about 100 mg/d), accounting for about 20% of the total uric acid in the body. It can be seen that the blood uric acid level is also greatly affected by diet. Under physiological conditions, the body's uric acid pool is 1200 mg, about 750 mg of uric acid is produced every day, and about 800~1000 mg is excreted, of which 30% is excreted from the intestines and bile duct, and 70% is excreted through the kidneys. The kidney is an important organ for uric acid excretion. If the renal creatinine clearance rate decreases by 5% to 25%, it can lead to hyperuricemia ( HUA). Under normal circumstances, the body's daily production and excretion of uric acid basically maintain a dynamic balance. Any factors that affect the production and excretion of serum uric acid can lead to an increase in serum uric acid levels. The maximum solubility of uric acid in the blood is 420 μmol/L. If this value is exceeded, urate will easily precipitate into crystals and deposit in tissues and cause inflammatory lesions, such as deposition in joints, causing the well-known gouty arthritis.

It is generally believed that asymptomatic hyperuricemia does not require treatment. But it doesn't mean we should just ignore it, because hyperuricemia is abnormal after all. Persistent high blood uric acid may cause uric acid crystals and urate crystals to deposit in the renal pelvis, ureter or renal tubules and renal interstitium, causing kidney damage and causing kidney stones. Therefore, the cause of high blood uric acid should be sought, such as diuretics, antihypertensive drugs, chemotherapy drugs and other drug factors, as well as kidney disease, blood disease, diabetes, etc., to find out the cause. At the same time, obesity, high-purine and high-calorie diet, alcoholism, excessive fatigue, mental stress, trauma, dampness and coldness and other inducing factors should be avoided. Lowering blood uric acid is beneficial and harmless.

The above is a detailed introduction to the dangers of high uric acid levels. If this happens, you must pay attention to your diet and reduce the choice of foods high in purine, otherwise the uric acid level will become higher, causing greater harm to the body. There are many ways to improve high uric acid levels, which can be done according to the patient's own situation.