Crescentic Glomerulonephritis: Seeing a doctor is like fighting a war

In life, patients with kidney disease are becoming more and more common. Many people have a certain understanding of kidney disease, but many people don’t know much about crescentic glomerulonephritis. So what is crescentic glomerulonephritis?

Rapidly progressive nephritis is undoubtedly the most dreaded kidney disease.

It is so terrifying because it is difficult to diagnose and even more difficult to treat. It takes about a few weeks to half a year for the patient to reach the level of uremia.

The disease is difficult to diagnose because it requires a renal biopsy to be confirmed, and patients are often in very poor condition when they seek medical treatment. Hypertension, edema, and renal failure make renal biopsy surgery very dangerous. In this case, whether to take the risk of performing a renal puncture or to let it go is a real test of the doctor's knowledge and conscience, and its difficulty is no less than Hamlet's "To be or not to be, that is the question." The reason is very simple. Whether it is rapidly progressive nephritis and the type of rapidly progressive nephritis are the basis and key to determining how to treat it.

The treatments for rapidly progressive nephritis include plasma exchange, methylprednisolone, cyclophosphamide and prednisone. All of these drugs and methods are powerful and powerful external martial arts that can break stones and split rocks. Their effects and side effects are equally surprising. Therefore, treating the disease without any basis for diagnosis often leads to serious systemic side effects. On the other hand, avoiding risks and letting things go their own way can result in irreversible kidney failure.

Even if a kidney biopsy is successful, it is only the first step in a long journey. The thrilling treatment that follows is likely to impress every doctor and patient. Pre-war decision-making, rapid response, and post-war evaluation all revolve around the comparison of side effects and effects (the situation of killing 1,000 enemies and injuring 800 of your own people can be seen at any time). Only the most compassionate and clinically experienced doctors can be competent for such a brutal battle.

The so-called "competence" does not mean the courage to die if you fail. Rapidly progressive nephritis is so ferocious that the fight against it is mostly doomed to failure. If you can't win, you can run away and get out safely, which makes you a hero on the battlefield, because the principle of fighting with the kidneys is not to endanger the life of the whole body. The order to retreat may be difficult for doctors and patients to accept at the time, but just like the "sacrifice tactic" in Go, a sense of the overall situation is a necessary prerequisite for doctors to overcome rapidly progressive nephritis. If an evacuation order is issued at the appropriate time and under the appropriate circumstances, the patient still has the opportunity to maintain life through dialysis and kidney transplantation.

Fortunately, the incidence of rapidly progressive nephritis is very low, and the above tests of water and fire are not common in our daily work.