What is the cause of high prostate acid phosphatase?

Prostatic acid phosphatase is a glycoprotein that hydrolyzes phosphate esters in the prostate secretion fluid. During the examination of prostate cancer, the index of this substance in the serum will increase significantly, which has a positive significance for the diagnosis of prostate cancer. It is also of great significance for monitoring the treatment effect of prostate cancer, whether there is recurrence or metastasis during the treatment process, and the patient's prognosis.

Clinical significance

In prostate cancer, serum PAP concentration increases significantly, and the degree of increase is basically parallel to the development of the tumor. When the condition improves, the PAP level decreases; when it rises again, it often indicates cancer recurrence, metastasis and poor prognosis.

The dangers of prostate cancer

One of the hazards of prostate cancer: systemic damage

Since cancer pain can affect the patient's diet, sleep, and spirit, the patient's overall condition will become increasingly weak over a long period of time, showing signs of weight loss and fatigue, and then developing a series of damaging symptoms such as anemia, cachexia, or renal failure.

The second hazard of prostate cancer: urination disorder

Urinary disorder is one of the most common symptoms of prostate cancer. About 80% of patients will experience progressive dysuria, thinning or deflected urine flow, bifurcated urine flow, prolonged urination, frequent urination, urgency, pain, and a feeling of incomplete urination due to the cancer. In severe cases, dribbling urine and urinary retention may occur. Only 3% of patients have hematuria.

The third hazard of prostate cancer: metastasis symptoms

Many tumors will metastasize in the late stages, and prostate cancer is no exception. About 1/3 or even 2/3 of prostate cancer patients have lymph node metastasis when they first seek medical treatment, mostly occurring in the iliac, iliac, waist, groin and other parts. It can cause swollen lymph nodes and swelling of the lower limbs in the corresponding areas. Hematogenous metastasis is often seen in bones (such as pelvis, sacrum, lumbar vertebrae, upper femur, etc.) and internal organs (such as lungs, liver, brain, adrenal glands, testicles, etc.).

Prostate cancer harm 4: pain

Approximately 31% of prostate cancer patients experience pain. Common pain areas are the lower back, sacrum, buttocks, and hips. Pelvic and sciatica pain are common symptoms of prostate cancer and are severe and unbearable. It may be caused by cancer metastasis to the bones or invasion of nerves or hydronephrosis or kidney infection.

The fifth harm of prostate cancer: infertility

If prostate cancer is not treated early, it may lead to male infertility.