What are the symptoms of bile duct sclerosis?

Biliary duct sclerosis is also relatively common. This disease often occurs in the elderly population. Most patients have a history of gallstones. Because of repeated biliary colic or jaundice, the patient's bile duct often gradually develops lesions, causing the bile duct to harden, leading to worsening of symptoms, etc. This is a relatively large threat to the patient's health and will aggravate some of the patient's symptoms.

What are the symptoms of bile duct sclerosis? This disease is more common in the elderly. Most patients have a history of gallstones, recurrent biliary colic and jaundice. Patients with cholangitis may have the typical triad of abdominal pain, jaundice, and high fever and chills.

Most patients have mild jaundice or a history of jaundice, or may have no jaundice. England et al. reported 25 patients, 19 of whom had a history of obstructive jaundice and 4 patients had a history of cholangitis. Myrian et al. reported 17 patients, of whom 12 had recurrent biliary colic, 10 had obstructive jaundice, and 6 had cholangitis.

In patients with Mirizzi syndrome, the gallbladder may enlarge, shrink, or remain unchanged. In most reports, the gallbladder shrinks. The common hepatic duct may be normal, widened, or narrow. If there is concurrent common bile duct stone/duodenal papillitis/stenosis, the common bile duct may be widened. In short, there are no specific changes in the gallbladder and bile duct.

The etiology and pathological basis of the disease are: the opening of the cystic duct is too low or parallel to the common bile duct; the walls of the two adjacent ducts are sometimes absent, separated only by a thin layer of fibrous membrane covered with bile duct epithelium; sometimes the surrounding tissue forms a sheath-like structure, wrapping the cystic duct and the common hepatic duct together. Once such stones become lodged in the cystic duct, they can easily compress the common hepatic duct, causing it to narrow or even form a fistula. Other possible factors include: 1. Gallstones incarcerated in the gallbladder neck or gallbladder duct, compression of the common hepatic duct by gallstones or inflammation, or inflammation involving the common hepatic duct. 2. Accompanied by pericholecystitis, there is severe inflammatory cell infiltration in the gallbladder triangle. 3. Due to the decrease in the number of neurons in the common bile duct wall, the common bile duct regulation is impaired.