Patchouli causes cancer

It is the dry ground part of the patchouli plant of the Lamiaceae family. Generally, the leaves and stems of wolf grass above the ground are used as medicine. So what are the side effects and taboos of the Chinese medicinal herb Patchouli? The editor below will explain it to you in detail.

It is the dry ground part of the patchouli plant of the Lamiaceae family. Generally, the leaves and stems of wolf grass above the ground are used as medicine. Patchouli has a pungent aroma and is slightly warm in nature; it enters the spleen, stomach, and lung meridians; it has the effects of aromatically clearing turbidity, strengthening the spleen, appetizing, and stopping vomiting, and relieving heat, and has been regarded as a fundamental medicine for treating summer heat and dampness by generations of Chinese medicine practitioners. In clinical medicine, it is mainly used to treat diseases such as dampness blocking the middle part of the body, abdominal distension and vomiting, summer-heat and dampness fatigue, chest tightness and shortness of breath, dampness and cold, abdominal pain and diarrhea, sinusitis and headache, dengue fever, dysentery, and bad breath. Take it by soaking, 3~9g.

Specific pharmacology and efficacy: Modern research shows that Patchouli contains a lot of volatile oils, which have an antispasmodic effect on the digestive tract, promote gastric acid secretion, and improve digestion and absorption capacity. Therefore, it has a certain effect on nausea and vomiting caused by poor appetite and indigestion. In addition, Patchouli can nourish the body, eliminate dampness, promote sweating and relieve heat, making it an ideal refreshing drink for summer. In spring and summer, you can pick its leaves and eat them. They are not only fragrant, but also have therapeutic health benefits.

1. Antifungal efficacy: Experiments have shown that Patchouli decoction (8%~15%) has an inhibitory effect on a variety of highly pathogenic bacteria such as Trichophyton thunbergii in test-tube babies. Medical ether extracts, alcohol extracts and water extracts can also inhibit a variety of highly pathogenic bacteria. The experiment showed that the antibacterial concentrations of Patchouli ether extract, alcohol extract, water extract and decoction against interdigital Trichophyton and plantar Trichophyton were 3%, 5%, 10% and 15%, respectively, indicating that the antibacterial ability of the extract was stronger than that of the decoction.

2. Anti-Neisseria meningitidis effect: Patchouli decoction has an inhibitory effect on Neisseria meningitidis when the concentration is 15 mg/ml; when the concentration rises to 31 mg/ml, it has an elimination effect on Neisseria meningitidis.

3. Antiviral therapeutic effect: Reports have emphasized that the flavonoids in Patchouli have antiviral therapeutic effects. The ingredients extracted from Patchouli can inhibit the growth and reproduction of rhinovirus, a gastrointestinal and respiratory pathogen. The ingredients in Patchouli with antiviral effects are flavonoids (flavonoid ingredients). The drug with stronger antiviral efficacy and easy to digest orally produced with this ingredient as the main ingredient is used for patients infected with rhinovirus, with good results.

4. Effects on the digestive tract: The volatile oil in Patchouli can stimulate the gastric mucosa, promote gastric acid metabolism, and promote digestion. However, the decoction of Patchouli has no effect on the gallbladder.

It is used in clinical medicine to treat summer diarrhea, damp-heat syndrome in the middle jiao, summer dermatitis, infantile diarrhea, and subacute catarrhal conjunctivitis.

Specific side effects and side effect production

1. Patchouli has a fragrant aroma and regulates qi. It is generally believed that long-term or large-scale consumption can easily damage the stomach, injure yin, and consume qi.

2. However, there are no independent reports of side effects caused by Patchouli, and there are many reports of allergic symptoms caused by pills and powders in prescriptions, such as Patchouli Zhengqi Water and Huodan Pills, which can cause allergic dermatitis and even shock reactions. Huoxiang Zhengqi Pills can also cause the cardiotoxic side effects of Aconitum, and can cause allergic symptoms such as allergic purpura, scarlet fever-like and measles-like drug eruptions, etc. In severe cases, it can cause anaphylactic shock, and external application can cause intestinal obstruction. There are reports that taking Huoxiang Zhengqi water internally for 10 minutes to 0.5 hours can cause dizziness, palpitations, sweating, followed by panic, shortness of breath, foaming at the mouth, and fainting. It can also cause allergic purpura, skin allergy rashes, etc.

3. There were 4 cases in which Huoxiang Zhengqi water could cause tachycardia, which should be taken seriously in clinical medicine.

4. Studies in recent years have shown that Patchouli has carcinogenic effects, because its volatile oil contains an ingredient called Patchouli (Gardenia also contains this ingredient, also known as pepper phenol methyl ether, which can be metabolized into 1'-methyl Patchouli in the body, which can produce DNA additives in the liver of mice. If 5.2ug of Patchouli molecules are injected into the subcutaneous tissue of mice for a total of 4 times, the incidence of hepatocellular carcinoma is 59% after one year. When 4.43ug of molecules are given, the incidence of hepatocellular carcinoma is 23%.

Specific precautions and taboos in production

1. "Compendium of Materia Medica": "It is forbidden to use in cases of yin deficiency and hyperactivity of fire, weak stomach and nausea, stomach heat and nausea, excessive fire and extreme heat in the middle burner, febrile disease and fever, and nausea and bloating caused by evil in the Yangming stomach."

2. Not suitable for long-term or excessive consumption.

3. There are many reports that Huoxiang Zhengqi Water can cause skin allergies. In order to reduce the occurrence of allergic symptoms, doctors should understand whether the patient has an allergic constitution before prescribing the medicine. For patients with allergic constitution or weak physical fitness, the medicine should be taken orally and the patients should be advised to take care of themselves.

4. If skin allergy occurs, stop taking the medicine immediately and treat it with other medications.