Can renal tubular damage be cured?

If the damage to the renal tubules is not serious, it can be self-healed through proper regulation. However, if it is serious, it may need to be treated through external means. However, it may not be completely cured. In severe cases, it may cause other diseases and lead to death. However, once renal tubular damage is discovered, active cooperation with treatment is still required. There are different methods at different stages:

1. Renal ischemia, poisoning and other factors may lead to renal tubular damage. Active treatment of the disease in the early stage and prevention of renal tubular necrosis are critical to the prognosis of the disease. Early renal tubular damage can be cured.

2. The renal tubule is a slender epithelial tubule connecting the wall of the renal capsule, which has both reabsorption and excretion functions. The renal tubules are divided into three parts according to their different morphological structures, distribution locations and functions: the proximal tubule, the loop of Medullary and the distal tubule.

3. The renal tubules have the functions of reabsorption, secretion and excretion. Ischemia, infection and toxins can cause degeneration and necrosis of renal tubular epithelial cells, leading to renal dysfunction.

① Treatment during the oliguria phase. The main focus is to adjust fluid balance, avoid hyperkalemia, actively prevent and treat uremia and metabolic acidosis, and treat infection.

②Eliminate the cause and treat the primary disease.

③Targeting the main links of the pathogenesis. The main links causing acute renal failure are sympathetic nerve excitement, massive release of catecholamines, renal ischemia, renal parenchymal damage, and finally renal failure. Therefore, preventive measures should include eliminating the causes and controlling the pathogenesis.

④Convalescence treatment. Strengthen your physical fitness, improve your nutrition, and exercise appropriately to promote early recovery of the body. Try to avoid all factors that are harmful to the kidneys, such as pregnancy, surgery, trauma, and drugs that are harmful to the kidneys. Check kidney function and urine routine regularly to observe kidney recovery. Generally, resting for half a year can restore the original physical condition. However, in a small number of patients, due to irreversible damage to the kidneys, develop into chronic renal failure, and they should be treated according to chronic renal failure.

5. A slight increase in urine NAG enzyme or a1 microglobulin or a weak positive urine glucose indicates renal tubular damage, but these indicators may be too sensitive in the general population, and their actual significance needs to be discussed in combination with clinical conditions. Therefore, it is recommended that you recheck these indicators after one month and observe for 3 months. Only if the indicators are abnormal after multiple rechecks will they have practical clinical significance. Medicines can cure diseases, but they can also cause diseases. Therefore, when the diagnosis is not very clear, most doctors will choose observation as the main approach rather than blindly using medication.

6. General treatment includes avoiding fatigue, removing predisposing factors such as infection, avoiding contact with nephrotoxic drugs or poisons, adopting a healthy lifestyle (such as quitting smoking, exercising moderately and controlling emotions, etc.) and a reasonable diet. During the acute phase, you should rest in bed and gradually increase your activity after the clinical symptoms improve. A low-salt diet (less than 3g per day) should be given during the acute phase. People with normal renal function do not need to limit protein intake, but in cases of azotemia, protein intake should be limited, and high-quality animal protein should be the main source. People with oliguria should limit their fluid intake.