Reasons for high astalt

High astalt mainly refers to high alanine aminotransferase, which is a common symptom in clinical practice. It is an important indicator of liver function. There are many reasons for its high level. It appears high in many hepatitis patients, which is mainly related to liver damage. In addition, when taking some anti-tumor drugs or anti-tuberculosis drugs, this indicator will also appear high because these drugs will cause certain damage to liver function.

Reasons for high astalt

Among the common factors, various types of hepatitis can cause elevated ALT, which is caused by liver damage. Some drugs, such as anti-tumor drugs and anti-tuberculosis drugs, can cause liver damage. Drinking large amounts of alcohol and eating certain foods can also cause short-term damage to liver function.

High aspartate aminotransferase (AST) indicates liver cell damage, which is generally seen in various hepatitis B, cirrhosis, fatty liver, alcoholic liver and other liver and gallbladder diseases. Further examination should be done to determine the cause of high aspartate aminotransferase and symptomatic treatment. Common causes of elevated transaminases:

1. Diseases of the liver itself

In particular, various types of viral hepatitis, cirrhosis, liver abscess, liver tuberculosis, liver cancer, fatty liver, hepatolenticular degeneration, etc. can all cause varying degrees of elevated transaminase levels.

2. Myocarditis

In addition to the liver, other organs and tissues in the body also contain this enzyme. Therefore, elevated blood transaminase levels may be seen in cases of myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, Japanese encephalitis, polymyositis, acute sepsis, typhoid fever, meningitis, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, crush syndrome, etc.

3. Gallbladder

Because transaminase is excreted from the bile duct, if there is a disease of the bile duct, gallbladder, or pancreas, or bile duct obstruction, the transaminase level may also increase.

4. Drug-induced or toxic liver damage

And drug allergy can cause elevated transaminase, often accompanied by cholestatic jaundice and hepatocellular damage. For example, when you are sick, you may take drugs that may damage the liver, such as erythromycin, tetracycline, sleeping pills, antipyretic analgesics, birth control pills, and Chinese medicines such as Pinellia, Areca, and Indigo. After these drugs are discontinued, transaminase levels return to normal rapidly.

Normal pregnancy, preeclampsia, acute fatty liver of pregnancy, etc. are also common causes of elevated transaminase. Certain other infectious diseases, such as pneumonia, typhoid fever, tuberculosis, infectious mononucleosis, etc. There are many reasons for a high alanine aminotransferase ratio, so if the alanine aminotransferase level is elevated, further examination should be conducted to find out the cause.