Causes 1. Pulmonary hamartoma The cause of the disease is still unclear. The more easily accepted hypothesis is that hamartomas are pieces of bronchial tissue that are inverted and shed during embryonic development and are surrounded by normal lung tissue. This part of tissue grows slowly, or may not grow for a certain period of time, and then gradually develops to form a tumor. The fact that most hamartomas occur after the age of 40 supports this hypothesis. 2. Renal Hamartoma The cause of the disease is still unclear. It often occurs in middle-aged women and is composed of mature adipose tissue, smooth muscle and abnormal blood vessels. 3. Hepatic Hamartoma Hepatic hamartomas are usually formed during the growth and development period and are tumors that grow along with the liver hilar structures. Some pathologists believe that it is likely that the primitive mesenchymal cells develop abnormally during the late embryonic period, when the liver forms lobules that connect to the bile ducts. 4. Hypothalamic Hamartoma Hypothalamic hamartoma, also known as gray tubercle hamartoma and hypothalamic neuronal hamartoma, is an extremely rare congenital abnormal development of brain tissue in clinical practice. 5. Breast Hamartoma Hamartoma of the breast, like hamartomas in other parts of the body, may be caused by structural disturbances in breast tissue during the embryonic period, which leads to changes in the proportions of normal breast structure. The residual mammary duct germs and fibrous and adipose tissues grow abnormally after birth, forming a benign tumor-like hyperplasia. When a tumor develops to a certain size, its growth rate will significantly slow down or stop. Some scholars also believe that breast hamartoma mainly occurs after childbirth or menopause and is related to hormonal changes that affect breast tissue. |
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