Is hyperthyroidism serious?

Hyperthyroidism is called "hyperthyroidism" because the thyroid gland synthesizes and releases excessive thyroid hormones, causing hypermetabolism and sympathetic nerve excitement, causing palpitations, sweating, increased eating and bowel movements, and weight loss. Is hyperthyroidism a serious disease? Most patients also often experience symptoms of exophthalmos, eyelid edema, and vision loss. Patients with hyperthyroidism should try to avoid mental stimulation or trauma and develop a good and regular life. Study and work habits, cultivate your own sentiments

diagnosis

The diagnosis of hyperthyroidism is not difficult. As long as hyperthyroidism is considered, a thyroid function test can be performed to diagnose it.

The secretion of T3, T4, FT3, and FT4 by the thyroid gland is significantly increased, and TSH is often reduced due to the feedback between the thyroid and pituitary axis. If a patient's T3, T4, FT3, and FT4 are elevated, while TSH is decreased, there is only one possibility, that is, hyperthyroidism.

Since most cases of hyperthyroidism are Graves' disease, an autoimmune disease of the thyroid gland, it is often accompanied by elevated thyroid autoantibodies, thyroglobulin antibodies, and thyroid peroxidase antibodies. Graves' disease patients have thyroid-stimulating immunoglobulin (TSI) produced by thyroid cells, so clinical tests show positive thyroid-stimulating hormone (TSH) receptor antibodies (TRAb).

Some patients with hyperthyroidism may only show elevated T3 and FT3, normal T4 and FT4, but decreased TSH, which we call "T3 hyperthyroidism." "T3 hyperthyroidism" is more common in elderly patients with hyperthyroidism or patients with toxic functional autonomous hot nodules.

Differential Diagnosis

There are also some inflammatory hyperthyroidism (or destructive hyperthyroidism) in clinical practice. It is caused by thyroid inflammatory reaction which leads to changes in the permeability of thyroid follicular cell membrane. A large amount of thyroid hormone is released into the blood from the follicular cells, causing a significant increase in thyroid hormone and a decrease in TSH in the blood. The clinical manifestations and biochemical tests are similar to hyperthyroidism. Inflammatory hyperthyroidism includes the hyperthyroidism stage of subacute thyroiditis, the hyperthyroidism stage of painless thyroiditis, the hyperthyroidism stage of postpartum thyroiditis and iodine-induced hyperthyroidism type 2. It is important to differentiate Graves' disease from inflammatory hyperthyroidism because the former requires aggressive treatment, while the latter does not. The biggest difference between the two is the thyroid 131I uptake rate test. The thyroid 131I uptake rate in the former is elevated or normal, while that in the latter is suppressed. In addition, the TRAb of the former is positive, while that of the latter is negative. The former is complicated with thyroid-related eye disease, while that of the latter is not.