What to do if your hands are allergic and have blisters

Many people will first develop small red rashes or blisters when they are allergic. Most of them include many types, such as viral ones, and some are just simple blisters. It is necessary to find the cause of the blisters based on the individual's physical condition. The condition of patients with allergic constitution is complicated, and each person is different. Active conditioning is needed to find the allergic factors, and then condition and treat them.

Nonallergic hypersensitivity is a term used to describe hypersensitivity reactions for which the immunological mechanism has not been demonstrated.

Allergic constitution

Overview

Generally, people who are prone to allergic reactions and allergic diseases but cannot find the cause of the disease are called "allergic constitution". People with "allergic constitution" may develop various allergic reactions and allergic diseases. For example, some suffer from eczema, urticaria, some suffer from allergic asthma, and some are particularly sensitive to certain drugs and may develop drug-induced dermatitis or even exfoliative dermatitis. However, occasional high reactivity to a known factor cannot be called "allergic constitution".

Causes of allergies

The causes of "allergic constitution" are complex and varied. It may be because children's skin is more delicate and can be caused by wind or exposure to sunlight. Therefore, be careful to avoid the above factors. In addition, pay proper attention to whether the child is breastfed, if he is breastfed. If the mother does not pay attention to her diet and eats fish and shrimp, it may cause allergies in children through breast milk. In this case, adults need to pay attention to their diet. Avoid foods that are prone to allergies, such as fish, shrimp, mushrooms, strawberries, flowers and plants, etc.

Characteristics of allergic constitution

From an immunological perspective, people with "allergic constitution" often have the following characteristics:

① Immunoglobulin E (IgE) is an antibody that mediates allergic reactions. The IgE content in normal human serum is extremely low, while the serum IgE content of some people with "allergic constitution" is 1,000 to 10,000 times higher than that of normal people.

② In normal people, there is a certain ratio between helper T cells 1 (Th1) and helper T cells 2 (Th2). The two cells coordinate to keep the body's immunity balanced. Th2 cells are often dominant in some people with "allergic constitution". Th2 cells can secrete a substance called interleukin-4 (IL-4), which can induce the synthesis of IgE and increase serum IgE levels.

③The normal human gastrointestinal tract has a variety of digestive enzymes, which can completely break down protein foods that enter the gastrointestinal tract before being absorbed into the blood. However, some people with "allergic constitutions" lack digestive enzymes, so the protein is absorbed into the blood without being fully broken down, allowing foreign proteins to enter the body and cause gastrointestinal allergic reactions. Such patients often also lack the protective antibody distributed on the surface of the intestinal mucosa - secretory immunoglobulin A (sIgA). The lack of such antibodies can cause intestinal bacteria to cause inflammation on the mucosal surface, thereby accelerating the intestinal mucosa's absorption of foreign proteins and inducing gastrointestinal allergic reactions.

④ The normal human body contains a certain amount of histamine enzyme, which has a destructive effect on the histamine released by certain cells during allergic reactions (which can cause smooth muscle contraction, capillary dilation, increased permeability, etc.). Therefore, even if a normal person has an allergic reaction to certain substances, the symptoms are not obvious. However, some people with "allergic constitution" lack histaminease and cannot destroy the histamine that triggers allergic reactions, resulting in obvious allergic symptoms.

The root causes of the above-mentioned immunological abnormalities are often closely related to genetics.