Drug-induced dermatitis

When it comes to diseases such as drug-induced dermatitis, many friends are not unfamiliar with it, because many friends have experienced large and small spots appearing on the skin all over the body after taking certain types of drugs, and even varying degrees of itching, etc. In severe cases, it may even be life-threatening. So what are the causes and treatments of drug-induced dermatitis?

In fact, the cause of drug-induced dermatitis is quite complicated. It is mainly due to drug resistance caused by taking certain types of drugs. Some friends have it because they take analgesics, some because they take antibiotics, etc. In short, not all people will have this type of drug resistance. So what is the treatment for drug-induced dermatitis?

Drug-induced dermatitis

Drug rash, also known as drug dermatitis, is an inflammatory reaction of the skin and mucous membranes caused by drugs entering the human body through oral, topical and injection routes. and

Adverse reactions caused by drugs are very complex and can be roughly divided into: drug overdose, intolerance, idiopathic, side effects, secondary effects and allergic reactions. Drug rash is the most common type of allergic reaction.

Causes

There are many types of drugs that cause drug rash, the most common types are as follows:

1. Antipyretic and analgesic drugs: pyrazolones and salicylates are the most common;

2. Sulfonamides: long-acting sulfonamides are the most common;

3. Hypnotic sedatives: barbiturates are the most common;

4. Antibiotics: Penicillin is the most common among them, and drug rashes caused by others such as furans and phenothiazines are also common.

5. Chinese herbal medicine: In recent years, the reports of drug rashes caused by Chinese herbal medicine have gradually increased. The drugs that cause allergies include single Chinese herbal medicines as well as compound preparations.

treat

1. Treatment principles

(1) Discontinue use of all suspected allergenic drugs and drugs with similar structures. (2) Drink more water or receive intravenous fluids to promote the excretion of drugs in the body. (3) Patients with mild symptoms should be given antihistamines, vitamin C and calcium supplements. In severe cases, glucocorticoids should be added. For particularly severe drug rashes, take various measures as early as possible. (4) Prevent and control secondary infection. (5) Supportive therapy, paying attention to fluid replacement and maintaining electrolyte balance. For patients with mucosal damage, the mucosa should be actively protected, especially the conjunctiva, to prevent corneal opacity and mucosal adhesion. Children should pay attention to the erosion of the glans and foreskin, which may cause foreskin stenosis. 2. Local treatment

For mild drug eruptions, local antipruritic measures can be used, the eroded surface can be adsorbed, and it can be kept clean and healed quickly. For severe drug eruptions, it is best to use dry exposure therapy (under an infrared lamp) or local revulol wet compresses or external application of PC cream, air disinfection, and the use of sterile sheets and bedding.

Regarding the treatment of drug-induced dermatitis, in addition to stopping taking all suspicious drugs in a timely manner, you also need to drink more water and use local antipruritic measures. Therefore, when you seek medical treatment, be sure to write down any obvious history of drug allergies in your medical record, so that the doctor can understand your physical condition better and avoid the occurrence of drug rash.