How to treat urticaria

There are many common diseases in life. Different diseases have some differences in symptoms and treatments. Therefore, when treating some diseases, you must first understand them, so that you can know what method to choose when treating them. Urticaria is a disease that seriously harms human health. After such a disease occurs, it must be treated in time. So how to treat urticaria?

Many people are not very clear about how to treat urticaria. There are also good methods to treat this type of disease. The following is a detailed introduction. However, when treating urticaria, be careful not to choose the treatment method at will.

How to treat urticaria:

1. General treatment

Because the causes of urticaria vary, the treatment effects are also different. The specific treatment measures are as follows:

(1) Eliminate the cause. Every patient should strive to find the cause of the attack and avoid it. If the cause is infection, the infected lesions should be treated actively. If the allergy is caused by drugs, the allergy medication should be stopped; if the allergy is caused by food, find out the allergic food and stop eating this food.

(2) Avoid triggering factors. For example, for cold urticaria, you should keep warm; for acetylcholine urticaria, you should reduce exercise, sweating and mood swings; for contact urticaria, you should reduce the chance of contact.

2. Medication

(1) Antihistamines ① H receptor antagonists

It has strong anti-histamine and anti-other inflammatory mediator effects, and is effective in treating all types of urticaria. Commonly used H1 receptor antagonists include diphenhydramine, cyproheptadine, chlorpheniramine, acrivastine, cetirizine, mizolastine, loratadine, ebastine, azelastine, desloratadine, etc.; when single treatment is ineffective, two different types of H1 receptor antagonists can be used in combination or in combination with H2 receptor antagonists. Commonly used H2 receptor antagonists include cimetidine, ranitidine, famotidine, etc. It is effective for acute, chronic urticaria and cold urticaria. Dosage varies from person to person. ② Doxepin

It is a tricyclic antidepressant that is particularly effective for chronic urticaria and has fewer adverse reactions. Doxepin is a better choice of drug for patients with urticaria who are not responsive to traditional antihistamines.

(2) Drugs that inhibit mast cell degranulation and reduce histamine release ① Meta-hydroxyisobutyrine sulfate is

β2-adrenergic receptor stimulators can increase the concentration of cAMP in the body, thereby inhibiting mast cell degranulation. ② Ketotifen

By increasing the concentration of cAMP in the body, it inhibits mast cell degranulation and prevents the release of inflammatory mediators (such as histamine, slow-reacting substances, etc.). Its inhibitory effect is stronger and faster than that of sodium cromoglycate, and it can be taken orally. ③Sodium cromoglycate can block the binding of antigen and antibody and inhibit the release of inflammatory mediators. If used in combination with glucocorticoids, the dosage of the latter can be reduced and the therapeutic effect can be enhanced. ④ Tranilast reduces the release of histamine by stabilizing the mast cell membrane.

(3) Glucocorticoids are second-line drugs for the treatment of urticaria. They are generally used when severe acute urticaria, urticarial vasculitis, and pressure urticaria are ineffective against antihistamines, or when chronic urticaria is severely stimulated. They are administered intravenously or orally, and long-term use should be avoided. Commonly used drugs are as follows: ① prednisone; ② triamcinolone; ③ dexamethasone; ④ diprosone. In emergency situations, hydrocortisone, dexamethasone, or methylprednisolone is given intravenously.

(4) Immunosuppressants: When patients with chronic urticaria have an autoimmune basis and the disease recurs, and the above treatments cannot achieve satisfactory results, immunosuppressants can be used. Cyclosporine has a good therapeutic effect. Azathioprine, cyclophosphamide, methotrexate and immunoglobulin can all be tried. Tripterygium wilfordii also has a certain therapeutic effect. Due to the high incidence of side effects of immunosuppressants, they are generally not recommended for the treatment of urticaria.

The above is a detailed introduction on how to treat urticaria. You can choose the above methods when treating this type of disease. However, when treating urticaria, you must also pay attention to understanding the patient's condition first. Otherwise, the wrong treatment method will not help the patient control the disease. This needs attention.