Causes of renal failure, so prevention is effective

The survey found that more and more patients are suffering from renal failure. Various nephrotoxic substances in life, such as drugs, bacterial endotoxins, heavy metal poisons and biological toxins, can cause disease by acting on the kidneys, but the pathogenesis of acute renal failure remains unclear.

1. What causes renal failure?

It is renal ischemia and renal poisoning. The continuous action of various factors that cause prerenal azotemia causes renal ischemia and hypoxia. Various nephrotoxic substances such as drugs, bacterial endotoxins, heavy metal poisons and biological toxins can cause disease when acting on the kidneys. In addition, incorrect blood transfusions and drugs can cause acute intravascular hemolysis, crush injuries, burns and severe myopathy, which can cause acute tubular necrosis and acute renal failure due to blockage of renal tubules by hemoglobin and myoglobin. The pathogenesis of acute renal failure is still unclear, and the theory of acute tubular injury cannot fully explain it. In recent years, it is believed that changes in renal hemodynamics caused by the disorder of the release of vasoconstrictor active substances, as well as cellular calcium influx and oxygen free radicals all play an important role in the pathogenesis of acute renal failure.

2. How to prevent renal failure?

1. Regulate the five internal organs

In daily life, we should maintain a regular diet and pay attention to hygiene to avoid invasion by external evils, especially in seasons and areas where infectious diseases are prevalent, we should strengthen preventive measures; do not eat spicy, roasted or greasy food to avoid the breeding of dampness and heat; regulate emotions, keep a happy spirit, make Qi and blood flow smoothly and avoid Qi stagnation and blood stasis; strengthen physical exercise to improve the body's defense capabilities.

2. Prevent poisoning

Relevant data show that 20% to 50% of acute renal failure is caused by drugs, and some is caused by exposure to harmful substances. Therefore, you should try to avoid using and contacting drugs or poisons that are toxic to the kidneys. If it is accidentally ingested or exposed, it should be discovered and treated early.

3. Timely prevention and treatment

Once the primary disease that induces acute renal failure occurs, early treatment should be sought, paying attention to expanding blood volume, correcting water and electrolyte disorders and acid-base imbalance, and restoring circulatory function. If the disease is found to be about to occur, measures should be taken early to replenish blood volume, increase cardiac output, restore renal perfusion and glomerular filtration rate, eliminate obstructions in the renal tubules, prevent and treat infection, and prevent damage to the renal parenchyma caused by DIC and renal ischemia. At the same time, the early use of blood-activating and blood-stasis-removing drugs can play a positive role in preventing the occurrence of this disease.