The hazards of acute pancreatitis, 4 major parts are the key

Acute pancreatitis is particularly common. Once patients show abnormalities, they must seek medical attention promptly, otherwise it will endanger organs such as the digestive system, heart, respiratory system, kidneys, nervous system, and blood system, and in severe cases it may even be life-threatening.

1. Harm to the digestive system : Whether it is mild pancreatitis or severe pancreatitis, various organs of the digestive system may change, such as abdominal pain, nausea, vomiting, gastrointestinal bleeding, jaundice, intestinal paralysis, intestinal obstruction, peritonitis, pseudocysts and abdominal abscesses, etc., which are more common and are well known to most patients, so this article will not go into details.

2. Damage to the heart : The heart may react to varying degrees during acute pancreatitis. In mild cases, there may only be symptoms such as increased heart rate and arrhythmia. In severe cases, myocardial infarction, cardiogenic shock, ventricular fibrillation and cardiac arrest may occur. Occasionally, pericarditis or pericardial effusion may occur, and even death due to pericardial tamponade may occur. Abnormal electrocardiogram during acute pancreatitis has its own impact, and we must also consider whether there is acute pancreatitis combined with heart disease. Therefore, we must pay attention to the medical history and corresponding examinations in order to make a correct judgment. Given that ECG abnormalities are common in acute pancreatitis, patients with acute pancreatitis should undergo routine ECG examinations, and those with abnormalities should undergo ECG monitoring, with timely review and follow-up.

3. Damage to the respiratory system : Respiratory complications are quite common in acute pancreatitis. About 70% of patients with acute pancreatitis have varying degrees of respiratory insufficiency. Respiratory system lesions in acute pancreatitis may make treatment difficult and are one of the main causes of early death in acute pancreatitis. The main pulmonary pathological manifestations of patients with severe acute pancreatitis are alveolar and interstitial edema, micro-atelectasis, alveolar hemorrhage and other changes. Patients who died within 1-2 weeks of the disease had lesions such as hyaline membrane coverage and epithelial cell hyperplasia in addition to the above-mentioned lesions.

4. Damage to the kidneys: Acute pancreatitis may be accompanied by kidney damage, but the degree of kidney damage may vary from patient to patient. Mild cases may only have mild abnormalities of renal tubular and glomerular function, while severe cases may develop fatal acute renal failure. Severe kidney damage is called pancreatic nephropathy, which occurs in up to 23% of severe acute pancreatitis and has a mortality rate of up to 50%. Therefore, the importance of timely treatment of renal dysfunction should be fully recognized. There are many causes of kidney damage, including shock and hypoxia, pancreatic nephrotoxins and immune complexes, which can all cause harm to the kidneys.

5. Harm to the nervous system : In patients with severe acute pancreatitis, a large amount of active proteolytic enzymes, phospholipase A, etc. enter the brain, which may damage brain tissue and blood vessels and cause a central nervous system damage syndrome, which is called pancreatic encephalopathy. Pancreatic encephalopathy is a common complication of severe acute pancreatitis, with an incidence of 35%. A study found that the incidence of pancreatic encephalopathy in acute pancreatitis was 9.18%, the mortality rate was 66.7%, and the incidence of pancreatic encephalopathy in severe cases was 7 times that of mild cases. The pathogenesis of pancreatic encephalopathy has not yet been fully elucidated. Most scholars believe that it is because a large amount of pancreatic enzymes escape into the blood circulation, causing cerebrovascular lesions, resulting in a variety of mental and neurological symptoms. In recent years, it has been gradually recognized that phospholipase A plays an important role in the occurrence of pancreatic encephalopathy.

6. Harm to the blood system : Acute pancreatitis may cause a variety of extrapancreatic manifestations, but changes in the blood system are relatively rare. Common changes in the blood system include: a sharp increase in white blood cell count, abnormal coagulation function, methemoglobinemia, skin ecchymoses, etc.

In summary, after the experts have talked about a series of relevant knowledge about the dangers of acute pancreatitis, in our daily lives, we should follow the doctor's advice, be sure to take care of the disease during treatment, exercise more often, avoid overeating, and rest on time.