What is the cause of high bile lipase?

High levels of cholesterase have a great impact on physical health. There are many reasons for high levels of cholesterase, including both genetic and acquired secondary reasons. When this index is high, it is particularly harmful to the patient's liver and can easily lead to worsening of liver disease. During the examination, if it is found to be high, it is important to understand why it is high and then treat it symptomatically. It has a relatively important examination significance clinically.

There are many reasons for high cholesterase levels, so we cannot generalize what to do when cholesterase levels are high. We need to decide based on the patient's condition. This requires patients to undergo further comprehensive examinations to find out the real cause of the high cholesterase level and treat it with symptomatic medication.

Finally, the doctor reminded that for patients with liver disease, whether it is liver function or other examination items that are abnormal, they should pay attention to it to avoid worsening of the disease!

Clinical significance:

1. Increase: seen in nervous system diseases, hyperthyroidism, diabetes, hypertension, bronchial asthma, type IV hyperlipoproteinemia, renal failure, etc. 2. Decrease: seen in organophosphorus poisoning, hepatitis, cirrhosis, malnutrition, pernicious anemia, acute infection, myocardial infarction, pulmonary infarction, muscle injury, chronic nephritis, dermatitis and late pregnancy, as well as intake of estrogen, cortisol, quinine, morphine, codeine, theobromine, aminophylline, barbiturates and other drugs.

Check significance

1. Acute viral hepatitis: The decrease in serum choline esterase is related to the severity of the disease, but not necessarily parallel to the degree of jaundice. If the activity continues to decrease, it often indicates a poor prognosis. 2. Chronic hepatitis: The activity of this enzyme does not change much in patients with chronic persistent hepatitis, and the activity of this enzyme in patients with chronic active hepatitis is similar to that in patients with acute hepatitis. 3. Liver cirrhosis: If the liver is in the compensatory stage, serum cholinesterase is usually normal. If the liver is in the decompensated stage, the activity of this enzyme decreases significantly. 4. In patients with subacute severe hepatitis, especially those with hepatic coma, serum cholinesterase levels are significantly reduced[3], and the reduction is often persistent. 5. In patients with extrahepatic biliary obstructive jaundice, serum cholinesterase is normal. If accompanied by biliary cirrhosis, the activity of this enzyme will decrease.