The dangers of high apolipoprotein B

The dangers of high apolipoprotein B

High levels of apolipoprotein B are harmful to the health of the body. It will cause abnormal blood lipid metabolism in the body, thus causing hyperlipidemia and atherosclerosis in patients. It is harmful to cardiovascular health and will increase the incidence of cardiovascular disease. There are many reasons for high levels of apolipoprotein B. In normal times, you must pay attention to diet and actively carry out good treatment.

The dangers of high apolipoprotein B

Apolipoprotein is the protein part of plasma lipoprotein, which can bind and transport blood lipids to various tissues of the body for metabolism and utilization. A large number of studies have found that mutations in apolipoprotein genes lead to polymorphisms of different alleles and further to apolipoproteins of different phenotypes, which can affect blood lipid metabolism and utilization, thereby affecting the occurrence and development of hyperlipidemia, atherosclerosis, cardiovascular and cerebrovascular diseases, etc.

Reasons for high levels: 1. Taking some anti-epileptic drugs can cause high levels of apolipoprotein a1, which will return to normal after stopping the drugs; 2. Long-term excessive drinking can cause high levels of apolipoprotein a1, so you must stop drinking at this time, and if you don't drink anymore, apolipoprotein a1 will return to normal; 3. Apolipoprotein a1 can also be high during pregnancy, which is a normal physiological phenomenon; 4. Liver abnormalities, such as chronic hepatitis, can cause high levels of apolipoprotein a1, and if not treated in time, it can easily turn into cirrhosis.

What is apolipoprotein b? The protein portion of plasma lipoproteins is called apolipoprotein. Apolipoproteins are the protein components that make up plasma lipoproteins and are mainly divided into five categories: a, b, c, d, and e. The basic function is to transport lipid substances and stabilize the structure of lipoproteins. Some apolipoproteins also have functions such as activating lipoprotein metabolic enzymes and recognizing receptors. They are mainly synthesized in the liver (and partly in the small intestine) and are named according to the ABC system, with each category further divided into several subcategories represented by Roman numerals. Apolipoprotein is an important component of plasma lipoprotein, which gives lipids a soluble form and plays an important role in plasma lipoprotein metabolism: 2.1. Promoting lipid transport; 2.2. Regulating enzyme activity; 2.3. Guiding plasma lipoprotein to bind to cell surface receptors. They are a group of plasma proteins that are extremely active in function. Apolipoprotein B exists on the surface of low-density lipoprotein, and cell recognition and uptake of LDL are mainly achieved through the recognition of apolipoprotein B.

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