Pain in the meridians throughout the body is generally caused by rheumatism, which often leads to joint pain, muscle soreness and other symptoms. Rheumatism is a systemic autoimmune disease, which is often hidden and takes a long time to develop. It has a certain genetic nature and should be treated with medication in time. For example, ibuprofen, diclofenac and other drugs can be used for treatment. Causes of rheumatism 1. Studies on endocrine factors have shown that the imbalance of estrogen and progesterone is related to the occurrence of various rheumatic diseases. 2. Genetic background: Research in recent years has shown that some rheumatic diseases, especially connective tissue diseases, are closely related to genetics and patient susceptibility and disease expression, which has certain significance for early or atypical cases and prognosis of the disease; among them, HLA (human tissue leukocyte antigen) is the most important. 3. Environmental and physical factors such as ultraviolet rays can induce SLE. 4. Infectious factors: According to years of research, a variety of infectious factors, antigens or superantigens produced by microorganisms can directly or indirectly stimulate or initiate immune responses. 5. Immune response: The body stimulates exogenous or endogenous antigens directly or through macrophage presentation, activating the corresponding T-cells. Some T-cells produce a large number of various inflammatory cytokines, causing varying degrees of damage or destruction to various tissues and organs; some T-cells then activate B-cells to produce a large number of antibodies, which directly or combine with antigens to form immune complexes, causing damage or destruction to tissues or organs. In addition, monocyte chemoattractant proteins (such as MCP-1) produced by monocytes can also participate in the inflammatory response. Most rheumatic diseases, either due to exogenous antigens produced by infection or endogenous antigens produced in the body, can initiate or aggravate this autoimmune response, and a variety of antibodies may appear in the serum. To sum up, the above content talks about why people get rheumatism? It can help people better understand rheumatism, and people should also actively treat rheumatism to avoid the harm of rheumatism to people. |
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