What is the cause of intermittent needle-like pain in the waist?

These include factors such as age, gender, occupation, socioeconomic status, dietary composition and structure, water intake, climate, metabolism and genetics. Upper urinary tract stones are common in people aged 20 to 50 years. There are more men than women. The peak age of onset in males is 35 years old. There are two peaks for women, at 30 and 55 years old. During World War II, the incidence of upper urinary tract stones decreased, but during the interval and in the past four decades, the incidence increased significantly, suggesting that it is related to changes in economic income and dietary structure. Experiments have shown that an increase in animal protein and refined sugar and a decrease in fiber in the diet promote the formation of upper urinary tract stones. Drinking plenty of water to dilute the urine can reduce the formation of crystals in the urine. High temperature and reduced activity are also influencing factors, but occupation and climate are not the sole determining factors.

Urine factors

Excessive excretion of stone-forming substances: increased excretion of calcium, oxalic acid, and uric acid in urine. Long-term bed rest, hyperparathyroidism (reabsorptive hypercalciuria), idiopathic hypercalciuria (absorptive hypercalciuria - increased intestinal calcium absorption or renal hypercalciuria - decreased tubular calcium reabsorption), other metabolic abnormalities and renal tubular acidosis all increase urinary calcium excretion. Gout, persistent acidic urine, chronic diarrhea and thiazide diuretics all increase uric acid excretion. Increased endogenous synthesis of oxalic acid or increased intestinal absorption of oxalic acid can cause hyperoxaluria.

Uric acid decreases and pH increases.

The decrease in urine volume increases the concentration of salts and organic substances.

The content of substances that inhibit crystal formation in urine is reduced, such as citric acid, pyrophosphate, magnesium, acidic mucopolysaccharides, and certain trace elements.

Anatomical abnormalities

For example, urinary tract obstruction may lead to the deposition of crystals or matrix in areas with poor drainage, urine retention and secondary urinary tract infection, which is conducive to stone formation.

Urinary tract infection

The cause of most calcium oxalate stones is unknown. Calcium phosphate and ammonium magnesium phosphate stones are associated with infection and obstruction. Uric acid stones are related to gout, etc. Cystine stones are a rare familial genetic disease caused by the excretion of large amounts of cystine in the urine.