Adrenaline injection

Adrenaline injection

Adrenaline injection is a hormone that people secrete for a long time. When people experience certain stimulation or other elements, it will cause adverse complications of adrenaline injection, so it will cause a lot of burden on the body. You must pay attention to the time when injecting adrenaline injection. It is necessary to use it symptomatically according to the symptoms and current pathological condition, otherwise it may cause side effects.

Basic Introduction: Epinephrine (adrenaline, epinephrine, abbreviated in capital letters: A or E) is the main hormone in the adrenal medulla. Its biosynthesis is mainly in the medullary chromium cells to first form norepinephrine, and then further through the action of phenylethanolamine N-methyl transferase (PNMT), norepinephrine is methylated to form epinephrine.

A hormone secreted by the human body. When people experience certain stimuli (such as excitement, fear, tension, etc.), this chemical is secreted, which can speed up their breathing (provide a large amount of oxygen), accelerate their heartbeat and blood flow, and dilate their pupils, providing more energy for physical activities and making reactions faster. Adrenaline is a hormone and neurotransmitter released by the adrenal glands. Adrenaline increases the heart's contractility, dilates the blood vessels in the heart, liver, tendons and bones, and constricts the blood vessels in the skin and mucous membranes. It is essential for saving dying people or animals.

Physical and chemical properties Chinese name: epinephrine

Chinese alias: Epinephrine tartrate; L-3,4-dihydroxy-α-((methylamino)methyl)benzyl alcohol D-tartrate

English Name:Epinephrine hydrogen tartrate

; Epinephrine Acid Tartrate; 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]; 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol 2,3-dihydroxybutanedioate (salt)

CAS No.:51-42-3

EINECS No.:200-097-1

Molecular formula:C9H13O3N

Molecular weight:183.204

InChI:InChI=1/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)

Boiling point: 413.1°C at 760 mmHg

Flash point: 207.9°C

Vapor pressure: 1.45E-07mmHg at 25°C

Product use: Mainly used for rescue of anaphylactic shock, bronchial asthma and cardiac arrest Dangerous goods signs:

Risk terms: R28:; R36/37/38:;

Safety terms: S26:; S28:; S36/37:; S45:;

During in vivo application, it is easily destroyed in alkaline intestinal fluid, intestinal mucosa, and liver, so it is ineffective when taken orally. Subcutaneous injection is absorbed slowly due to constriction of local blood vessels, and the effect can last for about 1 hour. Intramuscular injection is absorbed more quickly due to dilation of skeletal muscle blood vessels, and the effect can last for 10 to 30 minutes. The drug takes effect immediately after intravenous injection, but its effects last only a few minutes. In the body, it can be quickly taken up by noradrenergic nerve endings and metabolized by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO) in the tissues, and excreted through the kidneys, so its effect is short-lived.

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