Triamcinolone acetonide hydrochloride injection

Triamcinolone acetonide acetate injection is an injectable drug that is widely used in clinical medicine. It has a good promoting effect on some common diseases such as skin diseases, bronchial asthma, allergic dermatitis, synovitis, rheumatoid arthritis, etc. However, triamcinolone hydrochloride injection also has some adverse reactions and cannot be used by some special groups of people. The following is a detailed introduction to this drug.

1. Indications

Suitable for various skin diseases, allergic rhinitis, joint pain, bronchial asthma, periarthritis of the shoulder, tenosynovitis, synovitis, acute sprain, rheumatoid arthritis, etc.

2. Usage and Dosage

Intramuscular injection: once a week, 20-100 mg each time;

Intra-articular or subcutaneous injection: generally 2.5 to 5 mg per time.

3. Adverse Reactions

There are no obvious adverse reactions when glucocorticoids are used in physiological dose replacement therapy. Adverse reactions mostly occur when pharmacological doses are used, and are closely related to the course of treatment, dosage, type of medication, usage and route of administration. Common adverse reactions include the following:

1. Long-term use may cause the following side effects: iatrogenic Cushing's syndrome face and posture, weight gain, lower limb edema, purple striae, easy bleeding tendency, poor wound healing, acne, menstrual disorders, avascular necrosis of the humeral or femoral head, osteoporosis and fractures (including vertebral compression fractures, pathological fractures of long bones), muscle weakness, muscle atrophy, hypokalemia syndrome, gastrointestinal irritation (nausea, vomiting), pancreatitis, peptic ulcer or perforation, growth inhibition in children, glaucoma, cataracts, benign intracranial hypertension syndrome, impaired glucose tolerance and aggravated diabetes.

2. Patients may experience psychiatric symptoms: euphoria, agitation, delirium, restlessness, disorientation, and may also manifest as inhibition. Mental symptoms are prone to occur in people with chronic wasting diseases and those who have had mental disorders in the past.

3. Concurrent infection is the main adverse reaction of adrenal cortex hormones. The main pathogens are fungi, tuberculosis, Staphylococcus aureus, Proteus, Pseudomonas aeruginosa and various herpes viruses.

4. Glucocorticoid withdrawal syndrome. Sometimes patients experience dizziness, tendency to faint, abdominal or back pain, low fever, loss of appetite, nausea, vomiting, muscle or joint pain, headache, fatigue, and weakness after stopping the medication. If careful examination can rule out adrenal cortex insufficiency and recurrence of the original disease, it can be considered as a glucocorticoid dependence syndrome.

4. Taboos

It is contraindicated for those who are allergic to this product and steroid hormone drugs. It is generally not suitable for patients with the following diseases. In special circumstances, the pros and cons should be weighed and attention should be paid to the possibility of worsening of the condition: severe mental illness (past or present) and epilepsy, active peptic ulcer disease, recent gastrointestinal anastomosis, fracture, trauma repair period, corneal ulcer, hyperadrenocorticism, hypertension, diabetes, pregnant women, infections that cannot be controlled by antibiotics such as chickenpox, measles, fungal infections, severe osteoporosis, etc. This product contains

Benzyl alcohol is prohibited for intramuscular injection in children.