High thyroxine t4

An elevated thyroxine T4 does not mean anything. If only one T4 is elevated, it cannot confirm whether it is hyperthyroidism. This situation requires a combination of clinical and other examinations to make a diagnosis. In this case, it is best to go to the hospital to check the seven thyroid function tests. In daily life, you must develop good living habits, eating habits, eat less spicy and irritating foods, and maintain good sleep quality, which is good for your body.

The thyroid gland is like a factory that produces thyroid hormones, two of the most important types of which are thyroxine (T4) and triiodothyronine (T3). Thyroid hormones play an important role in metabolism, growth and development, and body temperature regulation. Therefore, both increased (hyperthyroidism, abbreviated as hyperthyroidism) and decreased (hypothyroidism, abbreviated as hypothyroidism) thyroid hormones will cause a series of changes in the body. If there is a problem with thyroid function, the related symptoms are usually distributed in various parts of the body and are not typical, so they can easily be ignored and misdiagnosed.

High thyroid hormone

Generally speaking, the main reason for high thyroid hormone is that the human body absorbs excessive iodine. Iodine can promote the secretion of thyroid hormone and aggravate the condition of patients with hyperthyroidism. All edible salt on the market is iodized salt. For people in some coastal areas, sometimes the body absorbs excessive iodine.

In hyperthyroidism, excessive secretion of thyroid hormones promotes the metabolism of nutrients such as fat and protein and accelerates oxidation. The body's heat production and heat dissipation increase significantly, and the basal metabolic rate increases abnormally, so energy must be increased every day to correct the body's energy consumption. Based on the above reasons, the diet of patients with hyperthyroidism must pay attention to high calories, high protein, high vitamins and supplements of calcium, phosphorus, potassium, zinc, magnesium, etc., in order to correct the consumption caused by hypermetabolism and improve the overall condition.

Effects of thyroid hormones

1. Promote growth and development

The growth-promoting effects of thyroid hormones are most evident during infancy, with the greatest impact occurring within the first four months of life. It mainly promotes the growth and development of bones, brain and reproductive organs. Without thyroid hormone, the pituitary GH cannot function. Moreover, when thyroid hormone is deficient, the pituitary gland's production and secretion of GH also decreases. Therefore, congenital or childhood lack of thyroid hormone causes cretinism. Cretinism patients have stagnant bone growth and are short in stature. The length ratio of the upper and lower body is abnormal, with the upper body accounting for a larger proportion than that of normal people. Due to the growth disorders of nerve cell dendrites, axons, myelin sheath and glial cells, the brain is not fully developed and mental retardation occurs. Their sexual organs also fail to mature. Patients must supplement thyroid hormone about three months after birth. After this period, treatment is often ineffective.

2. Impact on metabolism

Thermogenic Effect Thyroid hormones increase the rate of oxygen consumption in most tissues, increasing thermogenesis. This thermogenic effect may be due to the fact that thyroid hormones can increase the synthesis of Na+-K+ pumps on cell membranes and increase their activity, the latter of which is an energy-consuming process. Thyroxine increases the basal metabolic rate. 1 mg of thyroxine can increase heat production by 4000KJ. The basal metabolic rate of patients with hyperthyroidism can increase by about 35%, while the basal metabolic rate of patients with hypothyroidism can decrease by about 15%.

Its effects on the metabolism of the three major nutrients are very complex. In general, under normal circumstances, thyroid hormones mainly promote protein synthesis, especially significantly increasing protein synthesis in bones, skeletal muscles, liver, etc., which is of great significance for growth and development in childhood. However, excessive secretion of thyroid hormones will cause a large amount of protein breakdown, especially skeletal muscle protein, resulting in weight loss and weakness. In terms of sugar metabolism, thyroid hormones promote sugar absorption and the decomposition of liver glycogen. At the same time, it can also promote the utilization of sugar by peripheral tissues. In short, it accelerates the metabolism of sugar and fat, especially promotes the decomposition and oxidation process of sugar, fat and protein in many tissues, thereby increasing the body's oxygen consumption and heat production.

3. Other aspects

In addition, thyroid hormones also play an important role in the activities of some organs. It plays an important role in maintaining the excitability of the nervous system. Thyroid hormones can directly act on the myocardium, promote the release of Ca2+ from the sarcoplasmic reticulum, enhance myocardial contractility, and increase heart rate.