Some people go to the toilet soon after eating. At this time, you should pay attention to What's wrong with having a bowel movement after a meal? 1. Gastrointestinal motility disorders Changes in intestinal motility are an important pathophysiological basis for the occurrence of IBS symptoms. IBS patients with diarrhea as the main symptom showed signs of intestinal hypermotility, with a significantly shortened small intestinal transit time and significantly increased mean and maximum values of colon motility index and high-amplitude propulsive contractions. Constipation-type IBS is just the opposite, characterized by insufficient intestinal motility. 2. Visceral paresthesia Studies have found that most IBS patients have clinical characteristics of hypersensitivity to lumen (rectal) distension, with a decreased average pain threshold, increased discomfort after rectal distension, or abnormal visceral-somatic radiating pain, suggesting abnormal processing of visceral sensory signals at the spinal cord level. 3. Central paresthesia Studies have shown that the central pathways of visceral pain in IBS patients are different from those in normal people, and the brain response areas are also different between diarrhea-type IBS and constipation-type IBS. 4. Abnormal regulation of the brain-gut axis IBS patients have abnormalities in the central nervous system's processing of intestinal afferent signals and in the regulation of the enteric nervous system. 5. Intestinal infection and inflammatory response Studies have shown that the chance of developing IBS increases significantly after acute intestinal infection, so acute intestinal infection is considered to be one of the risk factors for inducing IBS. The relationship between mucosal inflammatory response, increased permeability and immune function activation caused by intestinal infection and the onset of IBS deserves further study. 6. Psychological factors IBS patients often have psychological abnormalities such as anxiety, tension, and depression. At the same time, mental and psychological stress can also induce or aggravate IBS symptoms, indicating that mental and psychological factors are closely related to IBS. |
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