What is gastric congestion and erosion?

Gastric congestion and erosion refers to the appearance of shallow ulcers in the gastric mucosa, which is a common and severe symptom of gastric ulcer. Clinically, it often leads to upper gastrointestinal bleeding and erosive gastritis in patients. When this happens, it is necessary to receive good treatment in time. It can be treated with drugs and other methods, and the diet should also be strengthened. Let’s take a look at this aspect.

What is gastric congestion and erosion?

1. Medication:

① Non-steroidal anti-inflammatory drugs, including aspirin, indomethacin (Indomethacin), etc. This type of drug can directly damage the gastric mucosa and inhibit cyclooxygenase damage. ②Anti-tumor drugs.

2. Stress:

Severe trauma, major surgery, extensive burns, intracranial lesions, sepsis, severe organ lesions and multiple organ failure can all cause this disease.

During stress: ① The release of adrenaline and norepinephrine increases, leading to gastric mucosal vasoconstriction and reduced blood flow. Mucosal ischemia causes insufficient secretion of mucus and sodium bicarbonate, decreased local prostaglandin synthesis and regeneration capacity, reduced gastric mucosal barrier function, and mucosal damage; ② Increased secretion of adrenal glucocorticoids leads to hypersecretion of gastric acid and enhanced mucosal invasion factors; ③ Weakened gastrointestinal motility and pyloric dysfunction can lead to reflux of bile and pancreatic juice, causing damage to the gastric mucosal barrier.

3. Alcohol:

The lipophilicity and fat-dissolving properties of alcohol lead to destruction of the gastric mucosal barrier, damage to epithelial cells, intramucosal bleeding and edema, and can also lead to hypersecretion of gastric acid and cause mucosal damage. The disease has a sudden onset, and upper gastrointestinal bleeding is the main clinical manifestation. Its incidence accounts for more than 1/4 of the causes of upper gastrointestinal bleeding, second only to peptic ulcer bleeding. In mild cases, only fecal occult blood is positive, while most patients have hematemesis and black stools. Bleeding occurs intermittently as the disease recurs. Usually the condition of this disease is more serious than peptic ulcer bleeding, and it is difficult to increase hemoglobin even after massive blood transfusion.