What causes liver necrosis?

What causes liver necrosis?

We have all heard of the word "darling". From this we can see that in our daily language we have put the liver on the same level as the heart. From this we can see that the liver is very important to us. If our diet is unhealthy, the liver will also react, and a common phenomenon is liver necrosis. So apart from diet, what exactly causes liver necrosis?

Hepatic necrosis is caused by one or more factors that cause a large number of liver cells to be damaged and necrotic over an unscheduled period of time. The integrity of the liver cell membrane is destroyed, the cytoplasmic membrane ruptures, and finally leads to cell lysis, death of intracellular organelles, and release of enzymes in the cytoplasm. It's not that the entire liver is damaged.

Symptoms of liver necrosis

Medical theory of liver necrosis:

Hepatic necrosis is the most serious type of viral hepatitis, which is often accompanied by multiple organ failure and has various clinical manifestations, which can be generally summarized into two aspects: one is the symptoms of hepatic necrosis; the other is the symptoms of hepatic necrosis of multiple other organs induced by hepatic necrosis, that is, the symptoms of important extrahepatic organs. .

Specific symptom classification

1. Symptoms of acute liver necrosis: nausea, vomiting, liver shrinkage, liver odor, etc.;

2. Symptoms of fulminant hepatic necrosis: loss of appetite, nausea, vomiting, jaundice, ascites, generalized bleeding, hepatic coma, cerebral edema, etc.

To sum up: For patients with the above symptoms, they should go to a regular liver disease hospital for further examination as soon as possible, make an accurate judgment, and then prescribe the right medicine. Do not rush to seek medical treatment and miss the best time for treatment.

What are the treatment principles for liver necrosis?

1. Anti-hepatocyte necrosis, promote hepatocyte repair and regeneration. (1) Strengthen supportive therapy. Rest in bed, strengthen nursing care, eat a balanced diet, take appropriate vitamin supplements, maintain water and electrolyte balance, and keep the internal environment stable. (2) Immunomodulatory treatment: ① Early use of adrenal cortical hormones and powerful hormone-like drugs such as glycines and antacids. This type of drug is an immunosuppressant that inhibits the immune response and prevents new liver cell necrosis. ②Immunomodulators: The application of thymosin can stimulate cellular immunity and regulate humoral immunity. (3) Improve microcirculation and prevent liver Kupffer cell failure. Compound salvia miltiorrhiza and scopolamine drugs (scopolamine, anisodine) can be used. (4) Prostaglandins (PGⅠ, PGⅡ): They protect the liver and kidneys and prevent the occurrence of hepatorenal syndrome.

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