Symptoms of Shehan syndrome

I believe that many people have never heard of or understood Sheehan syndrome. Although Sheehan syndrome is rarely heard of, it is a serious disease. Shehan's syndrome is a disease of hypopituitarism, which is mostly caused by acute necrosis of the anterior pituitary due to postpartum hemorrhage, shock, etc. This disease needs to be taken seriously and treated promptly. So what are the symptoms of Sheehan syndrome?

1. Symptoms of Sheehan syndrome

1. Prolactin deficiency causes no milk secretion or very little milk secretion after delivery and breast atrophy.

2. Growth hormone (GH) deficiency manifests as hypoglycemia, thyroid stimulating hormone (TSH) deficiency presents as myxedema, and adrenocorticotropic hormone (ACTH) deficiency presents as Addison's disease-like symptoms, hypotension, hypothermia, bradycardia, susceptibility to infection and concurrent shock, but sodium storage function is normal. Melanocyte-stimulating hormone (p-MsH) deficiency is particularly seen in depigmentation of the areola, axilla, and perineum.

3. Insufficient secretion of follicle-stimulating hormone, postpartum amenorrhea, loss of pubic and axillary hair, atrophy of breasts and genitals, decreased to disappearance of libido, and infertility.

4. Insufficient secretion of thyrotropin, hypothyroidism, fear of cold, fatigue, lack of sweat, constipation, memory loss, dry and rough skin, bradycardia, low blood pressure and slow reaction.

5. Insufficient secretion of adrenocorticotropic hormone, adrenal cortex dysfunction, anorexia, weight loss, hypotension, hypothermia, and in severe cases, a tendency to syncope.

2. Drug treatment

1. Adrenal cortical hormones: oral cortisone or hydrocortisone. For those with edema, use prednisone or dexamethasone instead. When there is infection, fever, trauma, or surgery, the dosage should be appropriately increased. 2. Thyroxine tablets: usually started taking a few days after taking adrenal cortex hormones. 3. Sex hormones: Artificial cycle therapy can be used: it is not necessary for those over middle age, while young patients can take diethylstilbestrol orally and add progesterone for the last 5 days. If menstruation occurs after stopping the drug for 3 to 7 days, it can be reused 5 days after bleeding.