Urticaria makes it itchier after taking Chinese medicine

There are many reasons that lead to urticaria. It may be a bacterial infection caused by poor immunity of the body, or it may be contact with something that makes you allergic. If you want symptomatic treatment, you must first understand what causes the allergy and then use medication. If the situation becomes more serious after taking Chinese medicine, you should stop taking it in time and choose other treatment methods.

If the condition gets worse after taking Chinese medicine, it means you are allergic to the medicine. To achieve a cure, the cause must be eliminated. It is recommended that you stop taking the Chinese medicine immediately.

treat

1. General treatment

Because the causes of urticaria vary, the treatment effects are also different. The specific treatment measures are as follows:

(1) Eliminate the cause

For each patient, efforts should be made to find the cause of the attack and avoid it. If the cause is infection, the infected lesions should be treated actively. If the allergy is caused by drugs, the allergy medication should be stopped; if the allergy is caused by food, find out the allergic food and stop eating this food.

(2) Avoid triggering factors

For example, for cold urticaria, you should keep warm; for acetylcholine urticaria, you should reduce exercise, sweating and mood swings; for contact urticaria, you should reduce the chance of contact.

2. Medication

(1) Antihistamines

①H receptor antagonists

It has strong anti-histamine and anti-other inflammatory mediator effects, and is effective in treating all types of urticaria. Commonly used H1 receptor antagonists include diphenhydramine, cyproheptadine, chlorpheniramine, acrivastine, cetirizine, mizolastine, loratadine, ebastine, azelastine, desloratadine, etc.; when single treatment is ineffective, two different types of H1 receptor antagonists can be used in combination or in combination with H2 receptor antagonists. Commonly used H2 receptor antagonists include cimetidine, ranitidine, famotidine, etc. It is effective for acute, chronic urticaria and cold urticaria. Dosage varies from person to person.

② Doxepin

It is a tricyclic antidepressant that is particularly effective for chronic urticaria and has fewer adverse reactions. Doxepin is a better choice of drug for patients with urticaria who are not responsive to traditional antihistamines.

(2) Drugs that inhibit mast cell degranulation and reduce histamine release

① Meta-hydroxyisobutyrine sulfate is

β2-adrenergic receptor stimulators can increase the concentration of cAMP in the body, thereby inhibiting mast cell degranulation.

② Ketotifen

By increasing the concentration of cAMP in the body, it inhibits mast cell degranulation and prevents the release of inflammatory mediators (such as histamine, slow-reacting substances, etc.). Its suppressed. It is stronger and faster than sodium cromoglycate and can be taken orally.

③Sodium cromoglycate

It can block the binding of antigen and antibody and inhibit the release of inflammatory mediators. If used in combination with glucocorticoids, the dosage of the latter can be reduced and the therapeutic effect can be enhanced.

④ Tranilast

Reduces histamine release by stabilizing mast cell membranes.

(3) Glucocorticoids are second-line drugs for the treatment of urticaria. They are generally used when severe acute urticaria, urticarial vasculitis, and pressure urticaria are ineffective against antihistamines, or when chronic urticaria is severely stimulated. They are administered intravenously or orally, and long-term use should be avoided. Commonly used drugs are as follows:

① Prednisone;

②Quanxilong;

③Dexamethasone;

④Get Baosong. In emergency situations, hydrocortisone, dexamethasone, or methylprednisolone is given intravenously.

(4) Immunosuppressants

When patients with chronic urticaria have an autoimmune basis, the disease recurs, and the above treatments cannot achieve satisfactory results, immunosuppressants can be used. Cyclosporine has a good therapeutic effect. Azathioprine, cyclophosphamide, methotrexate and immunoglobulin can all be tried. Tripterygium wilfordii also has a certain therapeutic effect. Due to the high incidence of side effects of immunosuppressants, they are generally not recommended for the treatment of urticaria. In addition, drugs that reduce vascular permeability, such as vitamin C, vitamin P, calcium supplements, etc., are often used in combination with antihistamines. If it is caused by infectious factors, appropriate antibiotics can be used for treatment.