Glucosamine sulfate

Medicine is very common. It is very helpful in treating diseases. Different medicines have very different effects on treating diseases. So before choosing a medicine, you should have a good understanding of all aspects of it. This will be of great help in treating diseases. Glucosamine sulfate is also very helpful in treating diseases.

However, many people are not very familiar with glucosamine sulfate. What diseases can it treat? When choosing such a drug, you also need to have a good understanding of it, so that when using it, you will know what disease it treats.

Glucosamine Sulfate:

Used to prevent and treat various types of osteoarthritis, such as osteoarthritis of the knee, hip, spine, shoulder, hand, wrist and ankle joints, as well as systemic osteoarthritis.

Pharmacology

1. Pharmacodynamics

Through the above-mentioned effects, this drug can directly fight inflammation, relieve the pain symptoms of osteoarthritis, improve joint function, and prevent the progression of osteoarthritis. And there will be no adverse reactions caused by the inhibition of prostaglandins.

2. Pharmacokinetics

90% of this drug is absorbed orally and is rapidly distributed in most tissues through biological barriers. It has a particular affinity for articular cartilage and can diffuse into the articular cartilage matrix and reach chondrocytes. The blood concentration reaches its peak 4 hours after taking the drug. 1-8 hours after taking glucosamine sulfate, increasing concentrations of the drug can be detected in the liver, kidneys, stomach wall, small intestine, brain, bones, muscles and articular cartilage, and this component decreases after 24 hours. The plasma protein binding rate is less than 10%. This drug is metabolized in the liver. 10% of the oral dose is excreted in the urine, 11% is excreted in the feces, and most of the rest is excreted in the form of carbon dioxide with exhaled air. The half-life is 18 hours.

Precautions

1. Contraindications: People who are allergic to glucosamine.

2. Use with caution is not yet clear.

3. Effects of drugs on pregnancy

In animal experiments, no adverse effects of this drug on reproductive function were observed. Due to the lack of human studies, pregnant women should use it under close medical supervision after weighing the pros and cons, and should avoid use in early pregnancy.

4. Effects of the drug on lactation In animal experiments, no adverse effects of this drug on lactation were observed. Due to the lack of human studies, breastfeeding women should use it after weighing the benefits and risks.

5. Check or monitor before, during and after medication

(1) Regularly monitor the patient's pain at rest or during exercise, ability to move freely, and walking distance.

(2) Radiographic evaluation (such as joint space narrowing).

(3) Routine blood biochemical examination.

Through the above introduction, we have a good understanding of glucosamine sulfate. It is very helpful in treating arthritis. Moreover, this drug is relatively simple to use and can be taken directly. The treatment of arthritis also requires a long time, so it is also necessary to make reasonable arrangements in daily life.