Roxithromycin side effects

When it comes to the drug roxithromycin, I believe many friends don’t know what type of drug it is. In fact, roxithromycin is one of the antibiotics with significant effects. Generally speaking, it can play a bactericidal and anti-inflammatory role, especially for pharyngitis, even sinusitis, or some respiratory diseases. The effect is very significant. But it is a drug after all, and it also has certain side effects. So what are the side effects of roxithromycin?

In fact, roxithromycin is not suitable for all kinds of people, because it is a very effective antibiotic. If the dose is too large or the method of taking is not right, it will cause various side effects. Therefore, it is best to consult a doctor before taking this type of medicine. So what are the side effects of roxithromycin?

Function and indications

Roxithromycin capsules are used for pharyngitis and tonsillitis caused by Streptococcus pyogenes, sinusitis, otitis media, acute bronchitis, acute exacerbation of chronic bronchitis caused by sensitive bacteria, pneumonia caused by Mycoplasma pneumoniae or Chlamydia pneumoniae; urethritis and cervicitis caused by Chlamydia trachomatis; skin and soft tissue infections caused by sensitive bacteria.

Roxithromycin side effects

The main adverse reactions are gastrointestinal reactions such as abdominal pain, diarrhea, nausea, and vomiting, but the incidence is significantly lower than that of erythromycin. Occasionally, rash, itchy skin, dizziness, headache, abnormal liver function (increased ALT and AST), and decreased peripheral blood cells may occur.

Precautions

1. Use with caution in patients with impaired liver function. The blood elimination half-life (t1/2b) of patients with severe cirrhosis is prolonged to more than twice the normal level. If it is really necessary to use it, 150 mg should be given once a day.

2. Patients with mild renal insufficiency do not need to adjust the dosage. Patients with severe renal insufficiency should double the dosing time (150 mg per dose, once a day).

3. This product has cross-resistance with erythromycin.

4. To obtain a higher blood concentration, this product needs to be taken with water on an empty stomach (1 hour before or 3 to 4 hours after a meal).

5. Follow up liver function regularly during medication.

As for the side effects of roxithromycin, you all already know about it. In fact, the side effects of erythromycin include abdominal pain, vomiting and other adverse symptoms. In addition, there may also be rashes, headaches, and even a decrease in peripheral blood cells. Therefore, when taking this type of medicine, it is best to consult a doctor in advance and never take it privately, otherwise various adverse symptoms and phenomena may easily occur, so everyone should pay attention.