Thyroiditis is a disease that is relatively difficult to cure. Most patients need to persist in long-term treatment before they will find that their bodies have improved. During this period, they must also pay attention to their dietary intake, eat more fresh vegetables and fruits, and avoid eating any high-fat foods, as these foods will damage their bodies and affect their treatment results. 1. Hashimoto’s thyroiditis Patients with mild thyroid enlargement and no symptoms may not need treatment but should be followed up and observed. When the thyroid gland is significantly enlarged or there is hypothyroidism, thyroid preparations should be given for treatment even if only serum TSH is elevated. If the thyroid gland enlarges rapidly or is accompanied by pain or compression symptoms, short-term glucocorticoid treatment can be used. Hashimoto's hyperthyroidism should be treated with low-dose antithyroid drugs, and iodine and surgery are generally not used to avoid severe hypothyroidism. 2. Subacute thyroiditis The main treatment is symptomatic treatment, reducing inflammation and relieving pain. Mild cases do not require treatment. For those with obvious symptoms, acetylsalicylic acid, nonsteroidal anti-inflammatory drugs, etc. can be used to relieve the symptoms. For more severe and prolonged cases, corticosteroids are recommended, and all symptoms will disappear within 24 to 48 hours. When thyroid radioiodine uptake returns to normal, treatment is terminated. Patients with obvious symptoms of thyrotoxicosis can use beta-blockers and do not need antithyroid drugs. When permanent hypothyroidism occurs, long-term replacement therapy is required. 3. Painless thyroiditis Symptomatic treatment is generally given during the thyrotoxicosis stage. β-blockers are used to alleviate thyrotoxicosis. Routine use of glucocorticoids is not required, and antithyroid drugs and radioactive iodine treatment should be avoided. Persistent hypothyroidism can be treated with thyroid hormone replacement therapy, and most patients can return to normal. The thyroid hormone dose needs to be adjusted until it is discontinued. 4. Postpartum thyroiditis Patients with severe hyperthyroidism symptoms can be given symptomatic treatment such as beta-blockers, and there is no need to use antithyroid drugs. When serum TSH is <10mIU/L during the hypothyroidism stage, thyroid hormone replacement therapy is not required and the patient can recover on his own. TSH should be monitored annually thereafter, and if hypothyroidism occurs, it should be treated promptly. During the thyrotoxicosis stage, serum T4 and T3 increase, the T3/T4 ratio is <20, and the thyroid iodine uptake rate is <3%. During the hypothyroidism period, thyroid hormone decreases; during the recovery period, T4, T3 and thyroid iodine uptake rate gradually return to normal. More than half of the patients were TgAb and TPOAb positive, and the increase of TPOAb was often more obvious. FANC examination showed lymphocyte infiltration. 4. Postpartum thyroiditis The characteristic laboratory test result of hyperthyroidism is that serum thyroid hormone levels and thyroid iodine uptake rate show a "two-way separation" phenomenon, that is, serum T4 and T3 levels are increased, and thyroid iodine uptake rate is significantly reduced. During the hypothyroidism stage, TSH levels gradually increase, while T4 and T3 levels decrease. During the recovery period, thyroid hormone levels and thyroid iodine uptake rate gradually return to normal. Ultrasonography shows hypoechoic or hypoechoic nodules. |
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