Can malaria kill people?

Malaria is no longer common in contemporary people's lives. It was relatively common in ancient times and was not a very easy to cure disease. At that time, contracting malaria could be life-threatening at any time. Therefore, those of us who often watch costume dramas are still very scared when we hear about malaria. We think it is a disease that can determine life or death, and children are especially prone to it.

Malaria, this terrible disease, many people are terrified. In this society where science is the mainstream, the rapid development of medicine is obvious to all of us. Science has cured many difficult and complicated diseases that could not be cured in the past. So, will malaria kill people in modern times?

Malaria is a disease caused by Plasmodium. Since there is no obvious inflammatory response around the parasitized hepatocytes, it is speculated that the infrared stage does not cause clinical symptoms in the host. Given that the onset of malaria symptoms coincides with the maturation of the erythrocytic stage of the Plasmodium, it is believed that the Plasmodium ingests hemoglobin in erythrocytes to produce metabolites and hemozoin. When the schizonts mature, they burst the erythrocytes and enter the bloodstream along with the merozoites, acting on the body's temperature regulation center to cause fever and other related symptoms.

The time of protozoan proliferation of different species is inconsistent, so the clinical attack cycle is also inconsistent. Generally, vivax malaria and ovale malaria occur every other day, quartan malaria occurs every two days, and falciparum malaria has irregular attacks due to the uneven development of protozoa. In addition, the increase in the intraerythrocytic schizonts of falciparum malaria parasites occurs in the visceral microvessels, which can easily cause visceral damage. If the attack is severe, it can cause congestion and edema of brain tissue; scattered hemorrhage spots and congestion in the white matter of the brain; significant congestion and edema of the pia mater, and in severe cases, the grooves and convolutions become shallow. Under the microscope, the capillaries are congested and contain a large number of red blood cells infected with malarial parasites and red blood cells that do not contain parasites but are aggregated. Circumferential hemorrhages, Durcl granulomas, focal desheathment, and degenerative lesions may also be seen. Other organs such as bone marrow, kidney, gastrointestinal tract, lung, heart, adrenal glands, etc. also have varying degrees of phagocyte proliferation, and can be seen phagocytosing red blood cells and hemochromatin containing malarial parasites. Red blood cells containing malarial parasites are found in the capillaries, and even in the microvessels, with endothelial shedding, degeneration and necrosis.

The above are the causes of malaria and possible complications obtained through medical research. With the understanding of the disease, as long as we treat it in time, treat it through the above causes, and prescribe the right medicine, malaria can be cured. In this era of advanced science, people will not die from malaria.