What are the effects of Datura?

What are the effects of Datura?

Many people use traditional Chinese medicine such as Datura to treat and regulate when they have asthma or cough. So what are the effects of Datura? In fact, each Chinese medicine has its own characteristics, many effects and medicinal values. Datura can not only relieve cough and asthma but also relieve pain. Therefore, it is often used to treat some respiratory diseases with good results.

The effects of Datura stramonium: Indications: Antitussive and antiasthmatic, analgesic and sedative. Asthma cough, cold pain in the abdomen, rheumatic pain, slow convulsions in children; surgical anesthesia.

1. "Compendium of Materia Medica": For all kinds of wind-induced and cold-damp beriberi, boil the decoction and wash the affected area. It is also used to treat epilepsy and rectal prolapse, and is also used as an anesthetic.

2. "Essentials of Raw Medicinal Herbs" says: Taking a small amount can relieve pain, open up the meridians and relieve headaches.

3. "Bencao Bian Du" (Compendium of Materia Medica): It can relieve pain from sores and ulcers, and relieve numbness, cold and asthma.

4. "Luchuan Materia Medica": Treats cough and pain caused by falls.

The role of Datura:

1. Effects on the central nervous system

① Effect on behavior: When scopolamine 6 mg/kg was injected into the lateral ventricle of rabbits, the rabbits closed their eyes, lay on their sides, and their righting reflex disappeared. The rabbits recovered after about 40 minutes, but their activities were still relatively low. Scopolamine and hibernation mixture can produce general anesthesia in humans, monkeys and dogs.

② Effect on EEG: When 0.05-0.1 mg/kg of scopolamine hydrobromide was injected intraperitoneally into conscious cats with buried electrodes, 5 minutes later, the EEG changed from low-amplitude fast waves to irregular high-amplitude slow waves. However, the startle reaction still exists at this time and the animal behaves quietly.

2. Effects on the circulatory system

① Effects on cardiovascular system: Scopolamine can relieve the inhibition of vagus nerve on the heart, making the sympathetic nerve dominant, thus accelerating the heart rate. Atropine has a similar effect, but is more potent.

② Effect on hemodynamics: Intravenous injection of datura alkaloids did not increase cardiac output in dogs with hemorrhagic shock. However, after blood transfusion to replenish blood volume, datura alkaloids could increase cardiac output. This shows that the effect of Datura stramonium on cardiac output is related to blood volume.

3. Effects on the respiratory system and smooth muscle organs

Small doses of Flos Datura injection can completely antagonize the contraction of isolated guinea pig tracheal smooth muscle induced by acetylcholine. Datura stramonium has an inhibitory effect on the tracheal mucous glands of rats with experimental tracheitis, and the goblet cells are significantly reduced, which is similar to the effect of cutting off the unilateral vagus nerve.

Through the above introduction, everyone is very clear about the effects of Datura. No kind of Chinese herbal medicine can be used casually. Even if the toxicity is very small, it may cause some trouble and harm to yourself if used improperly. Of course, during the medication period, you must take the medication on time and in the dosage prescribed by the doctor according to your specific condition, and do not take it lightly.

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