Anemia is a problem that we cannot ignore. People of all ages and genders should take care to prevent anemia, especially severe anemia, which may even cause myocardial hypoxia and heart failure, and cause hyperdestruction of blood cells and other adverse injuries. 1. Severe anemia can cause myocardial hypoxia and lead to heart failure On the other hand, the activation of myocardial energy sources requires the help of Vit B12. B12 deficiency can affect the activation of ATP, aggravate myocardial dysfunction and promote the occurrence of heart failure. Therefore, for patients with severe megaloblastic anemia, attention should be paid to the presence of cardiovascular disease at the beginning of treatment so that necessary measures can be taken to prevent accidents. 2. Bleeding: Due to thrombocytopenia and lack of other coagulation factors, bleeding is not uncommon in this disease, and sometimes cerebral hemorrhage or bleeding in other parts of the body may occur. The consequences of bleeding are serious. 3. Gout: Severe megaloblastic anemia can be seen in the ineffective hematopoiesis in the bone marrow caused by excessive blood cell destruction, resulting in abnormal increase in serum uric acid levels and causing gout attacks, but it is extremely rare. 4. Mental abnormality : Severe megaloblastic anemia can not only cause peripheral neuritis, but also mental abnormalities, such as excitement, depression, and even sleepwalking, which may be related to Vit It is related to abnormalities of brain nerve tissue caused by B12 deficiency. |
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