How to treat acanthosis nigricans? Drug treatment is effective!

Acanthosis nigricans is a relatively rare skin disease in clinical practice, so many people do not know how to treat it. The treatment of acanthosis nigricans is generally based on medication, which can be taken orally or applied topically. Attention should also be paid to diet for this disease.

1. Medication

First of all, before treating this disease, we must first find out the cause of the disease and eliminate it. Then you can use drugs for treatment: drug treatment can choose thyroxine, estrogen or corticosteroids. While receiving drug treatment, patients can be supplemented with some vitamin A and vitamin B.

2. External application

For patients whose skin lesions are not too serious, 0.05% vitamin A acid ointment or keratin peeling agent can be applied to the affected skin to remove the aged stratum corneum. If the skin lesions are more serious, physical therapy and cauterization can be considered for treatment.

3. Diet therapy:

A low-calorie, low-fat, higher-carbohydrate and fiber diet can help improve insulin sensitivity and improve hyperinsulinemia. After obese people control their diet, they lose weight and their body's insulin sensitivity improves.

4. Western medicine treatment

Systemic treatment: vitamin A 50,000 U, 3 times a day, for weeks or months. In malignant acanthosis nigricans, removal of the adenocarcinoma usually resolves skin symptoms. When the tumor recurs, skin symptoms often recur as well.

Topical application of moderate concentration keratolytic agents such as 10% sulfur coal tar ointment can be appropriate treatment for secondary bacterial or fungal infections.