How to treat cholestatic urticaria

The occurrence of cholealkaloid urticaria is often related to heat from exercise, mental stress, diet and other issues. It often manifests as papular wheals on the skin or red halos of varying sizes around them. Oral medications can be used to treat the problem.

1. It is mainly caused by the rise in deep body temperature after exercise, heat, mental stress , hot drinks or alcoholic beverages, which prompts acetylcholine to act on mast cells and cause the disease. It manifests as round papular wheals with a diameter of 2 to 4 mm that appear a few minutes after stimulation, surrounded by varying degrees of redness, which often spread to the upper trunk and upper limbs and do not merge with each other. The patient may feel itching, tingling or burning sensation, sometimes only severe itching without skin lesions, which may disappear within 0.5 to 1 hour. Occasionally, it is accompanied by systemic symptoms caused by acetylcholine (such as salivation, headache, bradypumping, pupil constriction, spasmodic abdominal pain, diarrhea), etc. Severe dizziness may lead to syncope. A skin test or scratch test with 1:5000 acetylcholine may produce a wheal at the injection site, with small satellite wheals around it.

II. Treatment

1. General treatment

Avoid triggers. Patients with cholestatic urticaria should keep their body cool, avoid sweating, heat, mental stress, hot drinks or alcoholic beverages, etc.

2. Oral medication

In addition to the regular use of antihistamines, atropine, propantheline, reserpine, etc. are often added to achieve more satisfactory therapeutic effects. Topical medications: In summer, you can choose anti-itching lotions, calamine lotion, etc. In winter, you can choose anti-itching emulsions (such as diphenhydramine cream).

prevention

Patients with cholestatic urticaria should keep their body cool, avoid sweating, heat, mental stress, hot drinks or alcoholic beverages, etc. Certain Chinese medicines, such as Polygonum multiflorum, wolfberry, ginseng, astragalus, ganoderma lucidum, jujube, Ligustrum lucidum, Cuscuta australis, Schisandra chinensis, Polygonatum sibiricum, Chinese yam, Codonopsis pilosula, etc., have multiple functions such as anti-free radicals, improving immune function, promoting metabolism, regulating the nervous system and endocrine system, and have obvious anti-allergic effects. People with allergies can choose one or two ingredients to make soup and drink as tea.