Classification of corticosteroids

Hormone drugs are mainly used to regulate the body's water and salt metabolism and sugar metabolism. For example, after entering the blood circulation, corticosteroids can promote reactions with specific proteins in the blood, thereby regulating the concentration of free steroids in the blood. There are generally five types of corticosteroids, such as sex hormones, adrenal cortex hormones, thyroid hormones, insulin, and five anterior pituitary hormones.

If classified by drug type, it can be divided into the following five categories:

1. Adrenal cortical hormones: including adrenocorticotropic hormone, glucocorticoids, and mineralocorticoids.

2. Sex hormones: including estrogens, progestins, androgens, anabolic hormones, and gonadotropins

3. Thyroid hormones: including thyroid stimulating hormone and thyroid hormones.

4. Insulin: including long-acting insulin, intermediate-acting insulin and short-acting insulin.

5. Anterior pituitary hormones: including growth hormones, somatostatins, growth hormone-releasing hormone (GHRH) and similar drugs, and adrenocorticotropic hormone-releasing hormone.

Clinical Application

① Adrenal cortex insufficiency.

②Autoimmune diseases.

③Allergic diseases.

④Inhibit rejection during organ transplantation.

⑤Infectious diseases.

⑥Shock.

⑦Tumor.

⑧Liver disease.

⑨Ophthalmological and skin diseases

. ⑩Myasthenia gravis. Auxiliary diagnosis of certain endocrine diseases. In short, corticosteroids are mainly used to rescue critically ill patients and treat certain chronic diseases that are not responsive to other drug treatments, such as rheumatoid arthritis and frequent asthma. Although it has definite antipyretic and analgesic effects, corticosteroids have too many serious adverse reactions.

Adverse Reactions

Corticosteroid hyperfunction; steroid diabetes; muscular atrophy and osteoporosis; inducing and aggravating infection; inducing and aggravating ulcers; inducing mental symptoms; concurrent eye diseases; teratogenicity; inappropriate drug withdrawal may also lead to cortical insufficiency, hormone withdrawal syndrome and symptom rebound.