Most people will have this problem of leukoplakia on the gums. It will not have much impact on their life and work. They will just feel a little abnormal when eating. Severe patients may also be affected in their normal eating. These are all closely related to leukoplakia on the gums. This situation may be caused by oral ulcers. A series of oral examinations should be done to find out the cause of the disease. pathology Epithelial proliferation, hyperkeratosis on the surface, most with hair-like protrusions, thickening of the spinous layer, ballooning degeneration of cells, concave cells, occasionally accompanied by mild atypical hyperplasia. PAS staining showed Candida albicans. EB virus can be seen under electron microscopy. Clinical manifestations Oral hairy leukoplakia lesions appear as white patches or irregular white wrinkles, forming a plush carpet-like appearance. The lesions vary in size, are difficult to wipe off, and may cause ulcers. It often occurs on the lateral edge of the tongue and is usually bilateral (so%). It is also found in the cheeks, floor of mouth, soft palate, gums and tonsils. Patients usually have no symptoms, or may experience burning sensation, pain, and decreased sense of taste. In addition, the patient also has symptoms of AIDS-related syndrome such as long-term low-to-moderate fever, fatigue, and positive HIV antibodies. diagnosis The diagnosis can be made based on systemic symptoms, oral manifestations, and positive HIV antibodies. treat High doses of the antiviral drugs acyclovir, desciclovir, and ganciclovir can temporarily control OHL. Azidothymidine (AZT), a drug that inhibits HIV reverse transcriptase, can cause OHL to regress. The most common sites for leukoplakia are the oral mucosa of the cheeks, back of the tongue, ventral tongue, lips, palate, floor of the mouth, gums, etc., but it can sometimes occur in other parts of the body. Some types have more specific locations: granular leukoplakia are mostly seen on the buccal mucosa at the corners of the mouth; wrinkled paper-like leukoplakia are mostly seen on the floor of the mouth and tongue; warty leukoplakia are mostly seen on the gums. The sites of vitiligo and white keratosis are different, and they have nothing in common in shape and texture. In addition to microabscesses and abnormal epithelial proliferation, Candida albicans leukoplakia can also be diagnosed with pathogens in the tissue by periodic acid-Schiff staining or culture. The site of onset, lesion texture, and clarity of lesion boundaries can be used to distinguish leukoplakia from white keratosis, and histological examination is more definitive. |
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