Is the mortality rate of septic shock high?

Septic shock is a relatively serious disease manifestation. When this disease occurs, it has a great impact on health. The mortality rate of septic shock is also relatively high compared with some other diseases. There are many causes of septic shock, which can cause multiple organ failure in patients. If it is not treated in time, it may lead to the death of patients.

Is the mortality rate of septic shock high?

Among the common causes of shock, septic shock is one of them. Many people do not know much about the harm of this disease. So what is the mortality rate of septic shock?

Septic shock refers to a syndrome of immune suppression disorders, microcirculation disorders, and damage to cell and organ metabolic functions caused by various pathogenic microorganisms and their metabolites. Once the patient's condition develops into septic shock, the risk of death is still considerable. However, in the past 20 years, with the development of medicine, the absolute mortality rate of patients with severe infection has dropped from 35.0% to 18.4%.

When infectious shock occurs, there is a decrease in effective circulating blood volume, microcirculation disorders, and tissue oxygen debt. Therefore, the treatment principles of shock include removing the cause of shock as soon as possible, restoring effective circulating blood volume as soon as possible, correcting microcirculation disorders, correcting tissue hypoxia, and preventing the occurrence of multiple organ dysfunction syndrome.

Treatment of septic shock

In the early stages of severe septic shock, large volumes of fluid resuscitation are often required. Once a severe infection is clinically diagnosed, active fluid resuscitation should be initiated as soon as possible, and early goal-directed treatment should be adopted. However, when life-threatening hypotension occurs in septic shock, vasoactive drugs are often needed early in addition to active fluid resuscitation to maintain mean arterial pressure > 65 mmHg to maintain perfusion of vital organs. Restoration of blood volume to normal or basic recovery of preload is a prerequisite for the use of vasoactive drugs.

For patients with severe septic shock and refractory hypotension, the use of small doses of vasopressin often has miraculous effects.

In severe infection states, the vascular responsiveness to catecholamines is reduced. Even after correcting acidosis, hypotension may still persist after the use of large doses of norepinephrine and dopamine. At this time, the administration of small doses of vasopressin can often stabilize hemodynamics, improve tissue perfusion, and produce a synergistic effect with other pressor drugs, thereby reducing the dosage of other pressor drugs. It often has miraculous effects in the treatment of septic shock.

Only by understanding the mortality rate of septic shock can we prevent this disease from harming our health. I believe that the above information has made this issue clear to you, so you must pay attention to it when the disease occurs.