High hemophagocytic granulocytes

There is an important type of white blood cell in the human body that has the function of killing bacteria and parasites in the body. It is the hemophagocytic granulocyte. Hemophagocytic granulocytes tend to be high when there are parasites, certain blood diseases or eczema in the body. The hemophagocytic granulocyte content must be kept within a certain range for the human body to remain healthy. If it is too high, it can cause a variety of diseases. Let us understand the harm that high levels of hemophagocytic granulocytes can cause to the human body.

1. Concept

Hemophagocytic granulocytes are generally shown as eosinophils in hospitals. Normal mature white blood cells in the human body can be divided into five categories: neutrophils, eosinophils, alkaliphils, lymphocytes and monocytes. Eosinophils are part of the white blood cells. Eosinophils have the function of killing bacteria and parasites, have a defensive function in the body, and are also extremely important cells in the immune response and allergic reaction process. In normal people, eosinophils account for 0-7% of the white blood cell count, and the direct count is (0.05-0.45)×109/L. The normal range of eosinophil reference values ​​for adults is (0.02-0.5)×109/L, accounting for 0.5%-5% of the total white blood cell count. When it exceeds the normal limit, it is called eosinophilia.

2. Causes

1.

Allergic diseases: bronchial asthma, drug allergy, urticaria, food allergy, angioedema, serum sickness, etc.

2.

Parasitic diseases: schistosomiasis, ascariasis, hookworm disease, etc.

3. Skin diseases: such as eczema, exfoliative dermatitis, pemphigus, psoriasis, etc.

4. Blood diseases: such as chronic myeloid leukemia, multiple myeloma, eosinophilic granuloma, etc.

5. Certain malignant tumors: certain epithelial tumors such as lung cancer.

6. Scarlet fever can cause eosinophilia.

7. Others: rheumatic diseases, hypopituitarism, allergic interstitial nephritis, etc.

Symptoms

Clinical manifestations are diverse and may include fever, cough, chest pain, palpitations, shortness of breath, neuropsychiatric symptoms, itching, rash, enlarged liver, spleen and lymph nodes, and edema of the extremities.

IV. Hazards

1. Allergic diseases such as bronchial asthma, urticaria, drug allergy, allergic purpura, etc.

2. Parasitic infections such as schistosomiasis, ascariasis, hookworm disease, etc.

3. Certain skin diseases such as eczema, exfoliative dermatitis, pemphigus, psoriasis, etc.

4. Certain blood diseases such as chronic myeloid leukemia, multiple myeloma, eosinophilic granuloma, etc.

5. Certain malignant tumors and certain epithelial tumors such as lung cancer.

6. Certain infectious diseases such as scarlet fever.

7. Other rheumatic diseases, hypopituitarism, adrenocortical insufficiency, allergic interstitial nephritis, etc.

5. Dietary precautions

Avoid spicy and irritating foods during the onset period.