Is venous sinus thrombosis serious?

Venous sinus thrombosis is a relatively special cerebrovascular disease. Infants and young adults are common groups of patients, and pediatric patients often develop lateral sinus and cavernous sinus infections. This is also a relatively serious disease, which is quite harmful to patients. It can easily lead to cerebral venous wall edema, cause local edema, cause venous infarction, affect the absorption of cerebrospinal fluid, and cause intracranial hypertension.

Is venous sinus thrombosis serious?

To better understand the clinical symptoms and signs of CVST, two different pathophysiological mechanisms should first be distinguished. That is, cerebral venous thrombosis - focal symptoms caused by venous obstruction; cerebral venous sinus thrombosis - intracranial hypertension caused by venous sinus thrombosis. In most patients, these two pathophysiological processes often exist simultaneously. Occlusion of cerebral veins produces localized cerebral edema and venous infarction.

Pathological examination may reveal enlarged, swollen veins, edema (including cytotoxic edema and vasogenic edema), ischemic neuronal damage and punctate hemorrhages. The latter can fuse into a large hematoma and be detected by CT. Transverse sigmoid sinus thrombosis can lead to increased venous pressure, thereby affecting the absorption of cerebrospinal fluid and causing intracranial hypertension.

Because the disease affects the final pathway of cerebrospinal fluid circulation, there is no pressure gradient between the subarachnoid space and the ventricles, so the ventricles do not expand and will not cause hydrocephalus in all patients.

Causes of sinus thrombosis 1. General manifestations The manifestations of inflammatory intracranial venous thrombosis are divided into systemic symptoms, symptoms of local infection foci and sinus symptoms. Systemic symptoms include irregular high fever, chills, fatigue, muscle aches, mental depression, subcutaneous congestion and other symptoms of infection and sepsis. Non-inflammatory intracranial venous thrombosis mainly includes symptoms of causes and risk factors and sinus symptoms. 2. The clinical manifestations of intracranial venous sinus thrombosis lack specificity, and its symptoms and signs vary. The onset may be acute or slow over several weeks. The most common symptoms include headache, focal neurological deficits, epileptic seizures, impaired consciousness, and optic disc edema.