Side effects of Isatis indigo

Isatis indigotica is a plant and also a traditional Chinese medicine. It has many benefits for the human body, such as improving people's body resistance, preventing cardiovascular diseases, clearing away heat and relieving fire, or relieving headaches and other symptoms. Although this drug has many benefits for the human body, it also has certain side effects, such as causing diarrhea, miscarriage, etc. The following is a detailed introduction to the side effects of Isatis indigotica.

The role of isatis indigo leaf:

1. Anti-pathogenic microorganisms

In vitro experiments show that the leaf of isatis has a broad-spectrum antibiotic effect. Its decoction has a certain degree of inhibitory effect on Staphylococcus aureus, Streptococcus A, meningococcus, Pneumococcus, Catarrhalis, Salmonella typhi, Escherichia coli, influenza bacillus, diphtheria bacillus and Shigella dysenteriae. The decoction of the roadside green leaf has a bactericidal effect on a variety of Shigella dysenteriae in the test tube; the experiment also shows that it has a good antibacterial effect on Shigella dysenteriae that are sensitive or resistant to syngeneic mycin, furazolidone, sulfathiazole and berberine. The leaf of isatis also has an inhibitory effect on Japanese encephalitis virus, mumps virus and influenza virus. It also has a killing effect on Leptospira.

2. Effects on the cardiovascular system

The decoction of Polygonum indigoferum leaves has an inhibitory effect on isolated toad hearts, which increases with increasing doses and can even cause cardiac arrest. It has a dilating effect on the blood vessels of the lower limbs of rats, and the dilating effect is particularly obvious when the blood vessels are in a contracted state.

3. Anti-inflammatory and antipyretic effects

Oral administration of 10g/kg of Polygonum indigoferum leaf decoction to rabbits can inhibit local skin inflammation caused by xylene and reduce capillary permeability. Oral administration of 5g/kg can reduce or accelerate the disappearance of formaldehyde-induced foot swelling in rats. Oral administration of 5-10g/kg can significantly reduce the body temperature of rabbits with fever caused by cholera and typhoid mixed vaccines.

Contraindications and side effects of Isatis indigo leaf

Contraindications:

People with weak spleen and stomach should not take it.

1. "Compendium of Materia Medica": "It should not be used on people with weak spleen and cold."

2. "Compendium of Materia Medica": "Do not use unless it is caused by heat and toxins in the heart and stomach."

3. "Depei Materia Medica": "It is forbidden to use in patients with diarrhea due to weakness."

Note:

In addition to the above two plants, which are used as medicinal isatis indigotica in most parts of the country, there are also some areas, such as Shanghai, where the leaves of Isatis indigotica of the Cruciferae family are used as isatis indigotica. Fujian, Guangxi, Guangdong and Sichuan use the leaves of Indigofera odorata in the family Acanthaceae as Isatis indigotica. In Jiangsu, Jiangxi, Hunan, Guizhou, and Guangdong (partial areas), the leaves of the Verbenaceae plant are used as isatis indigo leaves (the whole plant is used in Hengyang, Hunan). Fujian also uses the leaves of the Leguminosae plant as isatis indigo leaves. The above effects are the same as those of Polygonum tinctorium.

Side effects:

Isatis indigotica has the function of clearing away heat and purging fire. Taking it may cause diarrhea and may cause miscarriage in pregnant women.

Commonly used prescriptions of Isatis indigo leaf

1. Commonly used prescriptions 1. Prevention of Japanese encephalitis and meningitis: 25 grams of Isatis indigotica and 50 grams of soybeans, decocted in water, one dose per day, for seven consecutive days.

2. Treat Japanese encephalitis, meningitis, cold and fever, mumps: 25-50 grams of Isatis indigotica leaves and 50 grams of Lycopodiella cernua root. Take it in decoction, two doses per day.

3. Treat rashes caused by warm poison: 200 grams of indigo, 100 grams each of licorice and glue, and 8 he of fermented black beans. Use one dou of water to boil the two ingredients, take out three and a half liters, remove the dregs, add the fermented black beans and boil three times, remove the dregs, then add gelatin, divide into four doses, and drink up again. This treatment can last up to seven or eight days, and is very effective if sweating does not relieve the symptoms, or if vomiting or diarrhea causes excessive heat. (《Filling the gap at the back of the elbow》)

4. For treating high fever and headache, with pea-sized sores all over the body: 150g of Indigo, 27 Gardenias (split), 50g of Rhinoceros Horn (crushed), and 50g of Fermented Soybean. Cut the above four ingredients, add five liters of water, boil and take out two liters, divide into three doses, take it as you like. (Daqingtang from "Yannian Fang")